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Rapid Lead Discovery Through Iterative Screening of One Bead One Compound Libraries
[Image: see text] Primary hits that arise from screening one bead one compound (OBOC) libraries against a target of interest rarely have high potency. However, there has been little work focused on the development of an efficient workflow for primary hit improvement. In this study, we show that by c...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical
Society
2014
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294594/ https://www.ncbi.nlm.nih.gov/pubmed/25434974 http://dx.doi.org/10.1021/co500154e |