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Plumbagin elicits differential proteomic responses mainly involving cell cycle, apoptosis, autophagy, and epithelial-to-mesenchymal transition pathways in human prostate cancer PC-3 and DU145 cells

Plumbagin (PLB) has exhibited a potent anticancer effect in preclinical studies, but the molecular interactome remains elusive. This study aimed to compare the quantitative proteomic responses to PLB treatment in human prostate cancer PC-3 and DU145 cells using the approach of stable-isotope labelin...

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Detalles Bibliográficos
Autores principales:	Qiu, Jia-Xuan, Zhou, Zhi-Wei, He, Zhi-Xu, Zhao, Ruan Jin, Zhang, Xueji, Yang, Lun, Zhou, Shu-Feng, Mao, Zong-Fu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294653/ https://www.ncbi.nlm.nih.gov/pubmed/25609920 http://dx.doi.org/10.2147/DDDT.S71677

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