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The catalytically inactive tyrosine phosphatase HD-PTP/PTPN23 is a novel regulator of SMN complex localization
The survival motor neuron (SMN) complex fulfils essential functions in the assembly of snRNPs, which are key components in the splicing of pre-mRNAs. Little is known about the regulation of SMN complex activity by posttranslational modification despite its complicated phosphorylation pattern. Severa...
Autores principales: | Husedzinovic, Alma, Neumann, Beate, Reymann, Jürgen, Draeger-Meurer, Stefanie, Chari, Ashwin, Erfle, Holger, Fischer, Utz, Gruss, Oliver J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294665/ https://www.ncbi.nlm.nih.gov/pubmed/25392300 http://dx.doi.org/10.1091/mbc.E14-06-1151 |
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