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Prediction models in in vitro fertilization; where are we? A mini review

Since the introduction of in vitro fertilization (IVF) in 1978, over five million babies have been born worldwide using IVF. Contrary to the perception of many, IVF does not guarantee success. Almost 50% of couples that start IVF will remain childless, even if they undergo multiple IVF cycles. The d...

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Autores principales: van Loendersloot, Laura, Repping, S., Bossuyt, P.M.M., van der Veen, F., van Wely, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294714/
https://www.ncbi.nlm.nih.gov/pubmed/25685496
http://dx.doi.org/10.1016/j.jare.2013.05.002
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author van Loendersloot, Laura
Repping, S.
Bossuyt, P.M.M.
van der Veen, F.
van Wely, M.
author_facet van Loendersloot, Laura
Repping, S.
Bossuyt, P.M.M.
van der Veen, F.
van Wely, M.
author_sort van Loendersloot, Laura
collection PubMed
description Since the introduction of in vitro fertilization (IVF) in 1978, over five million babies have been born worldwide using IVF. Contrary to the perception of many, IVF does not guarantee success. Almost 50% of couples that start IVF will remain childless, even if they undergo multiple IVF cycles. The decision to start or pursue with IVF is challenging due to the high cost, the burden of the treatment, and the uncertain outcome. In optimal counseling on chances of a pregnancy with IVF, prediction models may play a role, since doctors are not able to correctly predict pregnancy chances. There are three phases of prediction model development: model derivation, model validation, and impact analysis. This review provides an overview on predictive factors in IVF, the available prediction models in IVF and provides key principles that can be used to critically appraise the literature on prediction models in IVF. We will address these points by the three phases of model development.
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spelling pubmed-42947142015-02-14 Prediction models in in vitro fertilization; where are we? A mini review van Loendersloot, Laura Repping, S. Bossuyt, P.M.M. van der Veen, F. van Wely, M. J Adv Res Mini Review Since the introduction of in vitro fertilization (IVF) in 1978, over five million babies have been born worldwide using IVF. Contrary to the perception of many, IVF does not guarantee success. Almost 50% of couples that start IVF will remain childless, even if they undergo multiple IVF cycles. The decision to start or pursue with IVF is challenging due to the high cost, the burden of the treatment, and the uncertain outcome. In optimal counseling on chances of a pregnancy with IVF, prediction models may play a role, since doctors are not able to correctly predict pregnancy chances. There are three phases of prediction model development: model derivation, model validation, and impact analysis. This review provides an overview on predictive factors in IVF, the available prediction models in IVF and provides key principles that can be used to critically appraise the literature on prediction models in IVF. We will address these points by the three phases of model development. Elsevier 2014-05 2013-05-09 /pmc/articles/PMC4294714/ /pubmed/25685496 http://dx.doi.org/10.1016/j.jare.2013.05.002 Text en © 2013 Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Mini Review
van Loendersloot, Laura
Repping, S.
Bossuyt, P.M.M.
van der Veen, F.
van Wely, M.
Prediction models in in vitro fertilization; where are we? A mini review
title Prediction models in in vitro fertilization; where are we? A mini review
title_full Prediction models in in vitro fertilization; where are we? A mini review
title_fullStr Prediction models in in vitro fertilization; where are we? A mini review
title_full_unstemmed Prediction models in in vitro fertilization; where are we? A mini review
title_short Prediction models in in vitro fertilization; where are we? A mini review
title_sort prediction models in in vitro fertilization; where are we? a mini review
topic Mini Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294714/
https://www.ncbi.nlm.nih.gov/pubmed/25685496
http://dx.doi.org/10.1016/j.jare.2013.05.002
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