Feasibility of optimizing trimetazidine dihydrochloride release from controlled porosity osmotic pump tablets of directly compressed cores

The aim of this study was to develop and optimize Trimetazidine dihydrochloride (TM) controlled porosity osmotic pump (CPOP) tablets of directly compressed cores. A 2(3) full factorial design was used to study the influence of three factors namely: PEG400 (10% and 25% based on coating polymer weight...

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Detalles Bibliográficos
Autores principales: Habib, Basant A., Rehim, Randa T. Abd El, Nour, Samia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294720/
https://www.ncbi.nlm.nih.gov/pubmed/25685502
http://dx.doi.org/10.1016/j.jare.2013.05.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294720/
https://www.ncbi.nlm.nih.gov/pubmed/25685502
http://dx.doi.org/10.1016/j.jare.2013.05.005

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