Application and evaluation of a molecular approach for detection of the schistosomicidal effect of Mirazid® (myrrh) in the murine model

The conventional PCR technique was used for studying the schistosomicidal effect of Mirazid® in the murine model. Results of the molecular study were compared with the parasitological results (ova and worm count). The used PCR technique was more sensitive than the Kato-Katz thick smears. Mirazid® sh...

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Detalles Bibliográficos
Autores principales: Lotfy, Wael M., Nageh, Aly M., Hussein, Neveen A., Hassan, Ashraf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294782/
https://www.ncbi.nlm.nih.gov/pubmed/25685466
http://dx.doi.org/10.1016/j.jare.2012.08.012
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author Lotfy, Wael M.
Nageh, Aly M.
Hussein, Neveen A.
Hassan, Ashraf A.
author_facet Lotfy, Wael M.
Nageh, Aly M.
Hussein, Neveen A.
Hassan, Ashraf A.
author_sort Lotfy, Wael M.
collection PubMed
description The conventional PCR technique was used for studying the schistosomicidal effect of Mirazid® in the murine model. Results of the molecular study were compared with the parasitological results (ova and worm count). The used PCR technique was more sensitive than the Kato-Katz thick smears. Mirazid® showed some schistosomicidal effects against murine Schistosoma mansoni. However, it was not efficient enough to cure any of the studied mice.
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spelling pubmed-42947822015-02-14 Application and evaluation of a molecular approach for detection of the schistosomicidal effect of Mirazid® (myrrh) in the murine model Lotfy, Wael M. Nageh, Aly M. Hussein, Neveen A. Hassan, Ashraf A. J Adv Res Short Communication The conventional PCR technique was used for studying the schistosomicidal effect of Mirazid® in the murine model. Results of the molecular study were compared with the parasitological results (ova and worm count). The used PCR technique was more sensitive than the Kato-Katz thick smears. Mirazid® showed some schistosomicidal effects against murine Schistosoma mansoni. However, it was not efficient enough to cure any of the studied mice. Elsevier 2013-11 2012-10-25 /pmc/articles/PMC4294782/ /pubmed/25685466 http://dx.doi.org/10.1016/j.jare.2012.08.012 Text en © 2012 Cairo University. Production and hosting by Elsevier B.V. All rights reserved. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Short Communication
Lotfy, Wael M.
Nageh, Aly M.
Hussein, Neveen A.
Hassan, Ashraf A.
Application and evaluation of a molecular approach for detection of the schistosomicidal effect of Mirazid® (myrrh) in the murine model
title Application and evaluation of a molecular approach for detection of the schistosomicidal effect of Mirazid® (myrrh) in the murine model
title_full Application and evaluation of a molecular approach for detection of the schistosomicidal effect of Mirazid® (myrrh) in the murine model
title_fullStr Application and evaluation of a molecular approach for detection of the schistosomicidal effect of Mirazid® (myrrh) in the murine model
title_full_unstemmed Application and evaluation of a molecular approach for detection of the schistosomicidal effect of Mirazid® (myrrh) in the murine model
title_short Application and evaluation of a molecular approach for detection of the schistosomicidal effect of Mirazid® (myrrh) in the murine model
title_sort application and evaluation of a molecular approach for detection of the schistosomicidal effect of mirazid® (myrrh) in the murine model
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294782/
https://www.ncbi.nlm.nih.gov/pubmed/25685466
http://dx.doi.org/10.1016/j.jare.2012.08.012
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