Sonochemical synthesis of 1,2,4,5-tetrasubstituted imidazoles using nanocrystalline MgAl(2)O(4) as an effective catalyst()

An efficient four-component synthesis of 1,2,4,5-tetrasubstituted imidazoles is described by one-step condensation of an aldehyde, benzil, ammonium acetate and primary aromatic amine with nanocrystalline magnesium aluminate in ethanol under ultrasonic irradiation. High yields, short reaction times,...

Descripción completa

Detalles Bibliográficos
Autores principales: Safari, Javad, Gandomi-Ravandi, Soheila, Akbari, Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294784/
https://www.ncbi.nlm.nih.gov/pubmed/25685459
http://dx.doi.org/10.1016/j.jare.2012.09.001
Descripción
Sumario:An efficient four-component synthesis of 1,2,4,5-tetrasubstituted imidazoles is described by one-step condensation of an aldehyde, benzil, ammonium acetate and primary aromatic amine with nanocrystalline magnesium aluminate in ethanol under ultrasonic irradiation. High yields, short reaction times, mild conditions, simplicity of operation and easy work-up are some advantages of this protocol.

Ejemplares similares