Sonochemical synthesis of 1,2,4,5-tetrasubstituted imidazoles using nanocrystalline MgAl(2)O(4) as an effective catalyst()

An efficient four-component synthesis of 1,2,4,5-tetrasubstituted imidazoles is described by one-step condensation of an aldehyde, benzil, ammonium acetate and primary aromatic amine with nanocrystalline magnesium aluminate in ethanol under ultrasonic irradiation. High yields, short reaction times,...

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Detalles Bibliográficos
Autores principales: Safari, Javad, Gandomi-Ravandi, Soheila, Akbari, Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294784/
https://www.ncbi.nlm.nih.gov/pubmed/25685459
http://dx.doi.org/10.1016/j.jare.2012.09.001
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author Safari, Javad
Gandomi-Ravandi, Soheila
Akbari, Zahra
author_facet Safari, Javad
Gandomi-Ravandi, Soheila
Akbari, Zahra
author_sort Safari, Javad
collection PubMed
description An efficient four-component synthesis of 1,2,4,5-tetrasubstituted imidazoles is described by one-step condensation of an aldehyde, benzil, ammonium acetate and primary aromatic amine with nanocrystalline magnesium aluminate in ethanol under ultrasonic irradiation. High yields, short reaction times, mild conditions, simplicity of operation and easy work-up are some advantages of this protocol.
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spelling pubmed-42947842015-02-14 Sonochemical synthesis of 1,2,4,5-tetrasubstituted imidazoles using nanocrystalline MgAl(2)O(4) as an effective catalyst() Safari, Javad Gandomi-Ravandi, Soheila Akbari, Zahra J Adv Res Original Article An efficient four-component synthesis of 1,2,4,5-tetrasubstituted imidazoles is described by one-step condensation of an aldehyde, benzil, ammonium acetate and primary aromatic amine with nanocrystalline magnesium aluminate in ethanol under ultrasonic irradiation. High yields, short reaction times, mild conditions, simplicity of operation and easy work-up are some advantages of this protocol. Elsevier 2013-11 2012-12-21 /pmc/articles/PMC4294784/ /pubmed/25685459 http://dx.doi.org/10.1016/j.jare.2012.09.001 Text en © 2012 Cairo University. Production and hosting by Elsevier B.V. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/3.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Original Article
Safari, Javad
Gandomi-Ravandi, Soheila
Akbari, Zahra
Sonochemical synthesis of 1,2,4,5-tetrasubstituted imidazoles using nanocrystalline MgAl(2)O(4) as an effective catalyst()
title Sonochemical synthesis of 1,2,4,5-tetrasubstituted imidazoles using nanocrystalline MgAl(2)O(4) as an effective catalyst()
title_full Sonochemical synthesis of 1,2,4,5-tetrasubstituted imidazoles using nanocrystalline MgAl(2)O(4) as an effective catalyst()
title_fullStr Sonochemical synthesis of 1,2,4,5-tetrasubstituted imidazoles using nanocrystalline MgAl(2)O(4) as an effective catalyst()
title_full_unstemmed Sonochemical synthesis of 1,2,4,5-tetrasubstituted imidazoles using nanocrystalline MgAl(2)O(4) as an effective catalyst()
title_short Sonochemical synthesis of 1,2,4,5-tetrasubstituted imidazoles using nanocrystalline MgAl(2)O(4) as an effective catalyst()
title_sort sonochemical synthesis of 1,2,4,5-tetrasubstituted imidazoles using nanocrystalline mgal(2)o(4) as an effective catalyst()
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294784/
https://www.ncbi.nlm.nih.gov/pubmed/25685459
http://dx.doi.org/10.1016/j.jare.2012.09.001
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