Valproic Acid-induced Hyperammonemic Encephalopathy Promoted by Levetiracetam

Encephalopathy resulting from the administration of levetiracetam (LEV) is a rare occurrence. We experienced a patient receiving LEV treated with valproic acid (VPA) for partial seizures with secondary generalization, following which she developed hyperammonemic encephalopathy and showed complete re...

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Detalles Bibliográficos
Autores principales: Roh, Sook Young, Jang, Hyun-soon, Jeong, Eun Hye, Kim, Byung-Su, Sunwoo, Moon Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Epilepsy Society 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295059/
https://www.ncbi.nlm.nih.gov/pubmed/25625094
http://dx.doi.org/10.14581/jer.14017
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author Roh, Sook Young
Jang, Hyun-soon
Jeong, Eun Hye
Kim, Byung-Su
Sunwoo, Moon Kyung
author_facet Roh, Sook Young
Jang, Hyun-soon
Jeong, Eun Hye
Kim, Byung-Su
Sunwoo, Moon Kyung
author_sort Roh, Sook Young
collection PubMed
description Encephalopathy resulting from the administration of levetiracetam (LEV) is a rare occurrence. We experienced a patient receiving LEV treated with valproic acid (VPA) for partial seizures with secondary generalization, following which she developed hyperammonemic encephalopathy and showed complete recovery after the drug was withdrawan. LEV is able to promote hyperammonemic encephalopathy when added to VPA.
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spelling pubmed-42950592015-01-26 Valproic Acid-induced Hyperammonemic Encephalopathy Promoted by Levetiracetam Roh, Sook Young Jang, Hyun-soon Jeong, Eun Hye Kim, Byung-Su Sunwoo, Moon Kyung J Epilepsy Res Case Report Encephalopathy resulting from the administration of levetiracetam (LEV) is a rare occurrence. We experienced a patient receiving LEV treated with valproic acid (VPA) for partial seizures with secondary generalization, following which she developed hyperammonemic encephalopathy and showed complete recovery after the drug was withdrawan. LEV is able to promote hyperammonemic encephalopathy when added to VPA. Korean Epilepsy Society 2014-12-31 /pmc/articles/PMC4295059/ /pubmed/25625094 http://dx.doi.org/10.14581/jer.14017 Text en Copyright © 2014 Korean Epilepsy Society This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Roh, Sook Young
Jang, Hyun-soon
Jeong, Eun Hye
Kim, Byung-Su
Sunwoo, Moon Kyung
Valproic Acid-induced Hyperammonemic Encephalopathy Promoted by Levetiracetam
title Valproic Acid-induced Hyperammonemic Encephalopathy Promoted by Levetiracetam
title_full Valproic Acid-induced Hyperammonemic Encephalopathy Promoted by Levetiracetam
title_fullStr Valproic Acid-induced Hyperammonemic Encephalopathy Promoted by Levetiracetam
title_full_unstemmed Valproic Acid-induced Hyperammonemic Encephalopathy Promoted by Levetiracetam
title_short Valproic Acid-induced Hyperammonemic Encephalopathy Promoted by Levetiracetam
title_sort valproic acid-induced hyperammonemic encephalopathy promoted by levetiracetam
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295059/
https://www.ncbi.nlm.nih.gov/pubmed/25625094
http://dx.doi.org/10.14581/jer.14017
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AT kimbyungsu valproicacidinducedhyperammonemicencephalopathypromotedbylevetiracetam
AT sunwoomoonkyung valproicacidinducedhyperammonemicencephalopathypromotedbylevetiracetam

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