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Oxidative Stress Associated with Neuronal Apoptosis in Experimental Models of Epilepsy

Epilepsy is considered one of the most common neurological disorders worldwide. Oxidative stress produced by free radicals may play a role in the initiation and progression of epilepsy; the changes in the mitochondrial and the oxidative stress state can lead mechanism associated with neuronal death...

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Autores principales: Méndez-Armenta, Marisela, Nava-Ruíz, Concepción, Juárez-Rebollar, Daniel, Rodríguez-Martínez, Erika, Yescas Gómez, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295154/
https://www.ncbi.nlm.nih.gov/pubmed/25614776
http://dx.doi.org/10.1155/2014/293689
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author Méndez-Armenta, Marisela
Nava-Ruíz, Concepción
Juárez-Rebollar, Daniel
Rodríguez-Martínez, Erika
Yescas Gómez, Petra
author_facet Méndez-Armenta, Marisela
Nava-Ruíz, Concepción
Juárez-Rebollar, Daniel
Rodríguez-Martínez, Erika
Yescas Gómez, Petra
author_sort Méndez-Armenta, Marisela
collection PubMed
description Epilepsy is considered one of the most common neurological disorders worldwide. Oxidative stress produced by free radicals may play a role in the initiation and progression of epilepsy; the changes in the mitochondrial and the oxidative stress state can lead mechanism associated with neuronal death pathway. Bioenergetics state failure and impaired mitochondrial function include excessive free radical production with impaired synthesis of antioxidants. This review summarizes evidence that suggest what is the role of oxidative stress on induction of apoptosis in experimental models of epilepsy.
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spelling pubmed-42951542015-01-22 Oxidative Stress Associated with Neuronal Apoptosis in Experimental Models of Epilepsy Méndez-Armenta, Marisela Nava-Ruíz, Concepción Juárez-Rebollar, Daniel Rodríguez-Martínez, Erika Yescas Gómez, Petra Oxid Med Cell Longev Review Article Epilepsy is considered one of the most common neurological disorders worldwide. Oxidative stress produced by free radicals may play a role in the initiation and progression of epilepsy; the changes in the mitochondrial and the oxidative stress state can lead mechanism associated with neuronal death pathway. Bioenergetics state failure and impaired mitochondrial function include excessive free radical production with impaired synthesis of antioxidants. This review summarizes evidence that suggest what is the role of oxidative stress on induction of apoptosis in experimental models of epilepsy. Hindawi Publishing Corporation 2014 2014-12-29 /pmc/articles/PMC4295154/ /pubmed/25614776 http://dx.doi.org/10.1155/2014/293689 Text en Copyright © 2014 Marisela Méndez-Armenta et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Méndez-Armenta, Marisela
Nava-Ruíz, Concepción
Juárez-Rebollar, Daniel
Rodríguez-Martínez, Erika
Yescas Gómez, Petra
Oxidative Stress Associated with Neuronal Apoptosis in Experimental Models of Epilepsy
title Oxidative Stress Associated with Neuronal Apoptosis in Experimental Models of Epilepsy
title_full Oxidative Stress Associated with Neuronal Apoptosis in Experimental Models of Epilepsy
title_fullStr Oxidative Stress Associated with Neuronal Apoptosis in Experimental Models of Epilepsy
title_full_unstemmed Oxidative Stress Associated with Neuronal Apoptosis in Experimental Models of Epilepsy
title_short Oxidative Stress Associated with Neuronal Apoptosis in Experimental Models of Epilepsy
title_sort oxidative stress associated with neuronal apoptosis in experimental models of epilepsy
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295154/
https://www.ncbi.nlm.nih.gov/pubmed/25614776
http://dx.doi.org/10.1155/2014/293689
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