Cargando…
Rab11a is required for apical protein localisation in the intestine
The small GTPase Rab11 plays an important role in the recycling of proteins to the plasma membrane as well as in polarised transport in epithelial cells and neurons. We generated conditional knockout mice deficient in Rab11a. Rab11a-deficient mice are embryonic lethal, and brain-specific Rab11a knoc...
Autores principales: | Sobajima, Tomoaki, Yoshimura, Shin-ichiro, Iwano, Tomohiko, Kunii, Masataka, Watanabe, Masahiko, Atik, Nur, Mushiake, Sotaro, Morii, Eiichi, Koyama, Yoshihisa, Miyoshi, Eiji, Harada, Akihiro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295169/ https://www.ncbi.nlm.nih.gov/pubmed/25527643 http://dx.doi.org/10.1242/bio.20148532 |
Ejemplares similares
-
Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis
por: Sato, Takashi, et al.
Publicado: (2014) -
The Rab GTPase-binding protein EHBP1L1 and its interactors CD2AP/CIN85 negatively regulate the length of primary cilia via actin remodeling
por: Iwano, Tomohiko, et al.
Publicado: (2023) -
EHBP1L1 coordinates Rab8 and Bin1 to regulate apical-directed transport in polarized epithelial cells
por: Nakajo, Atsuhiro, et al.
Publicado: (2016) -
The Rab11-binding protein RELCH/KIAA1468 controls intracellular cholesterol distribution
por: Sobajima, Tomoaki, et al.
Publicado: (2018) -
BIG1 is required for the survival of deep layer neurons, neuronal polarity, and the formation of axonal tracts between the thalamus and neocortex in developing brain
por: Teoh, Jia-Jie, et al.
Publicado: (2017)