Cargando…

Connexin43 enhances the expression of osteoarthritis-associated genes in synovial fibroblasts in culture

BACKGROUND: Recent work has shown that the gap junction protein connexin43 (Cx43) is upregulated in cells of the joint during osteoarthritis (OA). Here we examined if the OA-associated increase in Cx43 expression impacts the function of synovial fibroblasts by contributing to the production of catab...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gupta, Aditi, Niger, Corinne, Buo, Atum M, Eidelman, Eric R, Chen, Richard J, Stains, Joseph P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295231/ https://www.ncbi.nlm.nih.gov/pubmed/25496568 http://dx.doi.org/10.1186/1471-2474-15-425

Ejemplares similares

Connexin43 Mediated Delivery of ADAMTS5 Targeting siRNAs from Mesenchymal Stem Cells to Synovial Fibroblasts
por: Liu, Shuo, et al.
Publicado: (2015)

Interaction of connexin43 and protein kinase C-delta during FGF2 signaling
por: Niger, Corinne, et al.
Publicado: (2010)

A cost-effective method to enhance adenoviral transduction of primary murine osteoblasts and bone marrow stromal cells
por: Buo, Atum M, et al.
Publicado: (2016)

Axial strain enhances osteotomy repair with a concomitant increase in connexin43 expression
por: Gupta, Rishi R, et al.
Publicado: (2015)

Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
por: Varela-Eirín, Marta, et al.
Publicado: (2022)

Connexin43 Hemichannel-Mediated Regulation of Connexin43
por: Li, Kai, et al.
Publicado: (2013)

Expression and Function of Connexin 43 in Human Gingival Wound Healing and Fibroblasts
por: Tarzemany, Rana, et al.
Publicado: (2015)

Connexin 43 Controls the Astrocyte Immunoregulatory Phenotype
por: Boulay, Anne-Cécile, et al.
Publicado: (2018)

Connexin 26 and Connexin 43 in Canine Mammary Carcinoma
por: Luu, Savannah, et al.
Publicado: (2019)

Function of Connexin-43 in Macrophages
por: Rodjakovic, Daniel, et al.
Publicado: (2021)

Connexin 43 mediated gap junctional communication enhances breast tumor cell diapedesis in culture
por: Pollmann, Mary-Ann, et al.
Publicado: (2005)

Regulation of connexin 43 by interleukin 1β in adult rat cardiac fibroblasts and effects in an adult rat cardiac myocyte: fibroblast co-culture model
por: McArthur, Lisa, et al.
Publicado: (2019)

Internal translation of the connexin 43 transcript
por: Salat-Canela, Clàudia, et al.
Publicado: (2014)

The Role of Connexin 43 in Lung Disease
por: Swartzendruber, Julie A., et al.
Publicado: (2020)

Connexin 43 Hemichannels Regulate the Expression of Wound Healing-Associated Genes in Human Gingival Fibroblasts
por: Tarzemany, Rana, et al.
Publicado: (2017)

Connexin 43 plays a role in proliferation and migration of pulmonary arterial fibroblasts in response to hypoxia
por: McNair, Andrew J., et al.
Publicado: (2020)

Mechanotransduction of pulsatile stretch in a cell culture model of cardiac hypertrophy connexin 43 (Cx43) expression
por: Karl, S, et al.
Publicado: (2009)

Differential Metabotypes in Synovial Fibroblasts and Synovial Fluid in Hip Osteoarthritis Patients Support Inflammatory Responses
por: Farah, Hussein, et al.
Publicado: (2022)

Fluoxetin Upregulates Connexin 43 Expression in Astrocyte
por: Mostafavi, Hossein, et al.
Publicado: (2014)

Connexin 43 impacts on mitochondrial potassium uptake
por: Boengler, Kerstin, et al.
Publicado: (2013)

Connexin43 modulates neutrophil recruitment to the lung
por: Sarieddine, Maya Z Richani, et al.
Publicado: (2009)

The Importance of Connexin 43 in Enamel Development and Mineralization
por: Al-Ansari, Sali, et al.
Publicado: (2018)

Connexin 43: An Interface Connecting Neuroinflammation to Depression
por: Jiang, Hong, et al.
Publicado: (2023)

Connexin 43 Phosphorylation: Implications in Multiple Diseases
por: Zhang, Meng, et al.
Publicado: (2023)

HMGB1–LPS complex promotes transformation of osteoarthritis synovial fibroblasts to a rheumatoid arthritis synovial fibroblast-like phenotype
por: Qin, Y, et al.
Publicado: (2014)

HepaCAM associates with connexin 43 and enhances its localization in cellular junctions
por: Wu, Meihui, et al.
Publicado: (2016)

Connexin 32 and connexin 43 are involved in lineage restriction of hepatic progenitor cells to hepatocytes
por: Pei, Haiyun, et al.
Publicado: (2017)

Hippocampal Expression of Connexin36 and Connexin43 during Epileptogenesis in Pilocarpine Model of Epilepsy
por: Motaghi, Sahel, et al.
Publicado: (2017)

Connexin26 mutations causing palmoplantar keratoderma and deafness interact with connexin43, modifying gap junction and hemichannel properties
por: Shuja, Zunaira, et al.
Publicado: (2016)

The potency of the fs260 connexin43 mutant to impair keratinocyte differentiation is distinct from other disease-linked connexin43 mutants
por: Churko, Jared M., et al.
Publicado: (2010)

VIP and CRF reduce ADAMTS expression and function in osteoarthritis synovial fibroblasts
por: Pérez‐García, Selene, et al.
Publicado: (2016)

Dishevelled-2 modulates osteogenic differentiation of human synovial fibroblasts in osteoarthritis
por: Zhang, Lihua, et al.
Publicado: (2018)

Epigenetic modifications of interleukin-6 in synovial fibroblasts from osteoarthritis patients
por: Yang, Fei, et al.
Publicado: (2017)

Morphine Induces Fibroblast Activation through Up-regulation of Connexin 43 Expression: Implication of Fibrosis in Wound Healing
por: Wu, Ping-Ching, et al.
Publicado: (2018)

Squid Ink Polysaccharides Protect Human Fibroblast Against Oxidative Stress by Regulating NADPH Oxidase and Connexin43
por: Chen, Ying, et al.
Publicado: (2020)

IL-6 secretion in osteoarthritis patients is mediated by chondrocyte-synovial fibroblast cross-talk and is enhanced by obesity
por: Pearson, Mark J., et al.
Publicado: (2017)

A protocol for the culture and isolation of murine synovial fibroblasts
por: Zhao, Jinjun, et al.
Publicado: (2016)

GJA1 (connexin43) is a key regulator of Alzheimer’s disease pathogenesis
por: Kajiwara, Yuji, et al.
Publicado: (2018)

Transfected connexin45 alters gap junction permeability in cells expressing endogenous connexin43
Publicado: (1995)

Connexin43 and connexin50 channels exhibit different permeability to the second messenger inositol triphosphate
por: Valiunas, Virginijus, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_rrdnjlda29v2dv2m2brgc7eeaq