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Establishment of the neurogenic boundary of the mouse retina requires cooperation of SOX2 and WNT signaling
BACKGROUND: Eye development in vertebrates relies on the critical regulation of SOX2 expression. Humans with mutations in SOX2 often suffer from eye defects including anophthalmia (no eye) and microphthalmia (small eye). In mice, deletion of Sox2 in optic cup progenitor cells results in loss of neur...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295269/ https://www.ncbi.nlm.nih.gov/pubmed/25488119 http://dx.doi.org/10.1186/1749-8104-9-27 |