Ontogeny of CpG island methylation and specificity of DNMT3 methyltransferases during embryonic development in the mouse

BACKGROUND: In the mouse, the patterns of DNA methylation are established during early embryonic development in the epiblast. We quantified the targets and kinetics of DNA methylation acquisition in epiblast cells, and determined the contribution of the de novo methyltransferases DNMT3A and DNMT3B t...

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Detalles Bibliográficos
Autores principales: Auclair, Ghislain, Guibert, Sylvain, Bender, Ambre, Weber, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295324/
https://www.ncbi.nlm.nih.gov/pubmed/25476147
http://dx.doi.org/10.1186/s13059-014-0545-5

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