The orthotopic xenotransplant of human glioblastoma successfully recapitulates glioblastoma-microenvironment interactions in a non-immunosuppressed mouse model

BACKGROUND: Glioblastoma (GBM) is the most common primary brain tumor and the most aggressive glial tumor. This tumor is highly heterogeneous, angiogenic, and insensitive to radio- and chemotherapy. Here we have investigated the progression of GBM produced by the injection of human GBM cells into th...

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Detalles Bibliográficos
Autores principales: Garcia, Celina, Dubois, Luiz Gustavo, Xavier, Anna Lenice, Geraldo, Luiz Henrique, da Fonseca, Anna Carolina Carvalho, Correia, Ana Helena, Meirelles, Fernanda, Ventura, Grasiella, Romão, Luciana, Canedo, Nathalie Henriques Silva, de Souza, Jorge Marcondes, de Menezes, João Ricardo Lacerda, Moura-Neto, Vivaldo, Tovar-Moll, Fernanda, Lima, Flavia Regina Souza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295410/
https://www.ncbi.nlm.nih.gov/pubmed/25482099
http://dx.doi.org/10.1186/1471-2407-14-923

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