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From transcriptional regulation to drugging the cancer epigenome
Jay Bradner discusses the opportunities and challenges for the study and therapeutic targeting of the cancer epigenome, as well as innovative approaches to drug discovery.
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295578/ https://www.ncbi.nlm.nih.gov/pubmed/25593599 http://dx.doi.org/10.1186/s13073-014-0123-1 |
| _version_ | 1782352868588650496 |
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| author | Bradner, James E |
| author_facet | Bradner, James E |
| author_sort | Bradner, James E |
| collection | PubMed |
| description | Jay Bradner discusses the opportunities and challenges for the study and therapeutic targeting of the cancer epigenome, as well as innovative approaches to drug discovery. |
| format | Online Article Text |
| id | pubmed-4295578 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2014 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-42955782015-01-16 From transcriptional regulation to drugging the cancer epigenome Bradner, James E Genome Med Q and A Jay Bradner discusses the opportunities and challenges for the study and therapeutic targeting of the cancer epigenome, as well as innovative approaches to drug discovery. BioMed Central 2014-12-20 /pmc/articles/PMC4295578/ /pubmed/25593599 http://dx.doi.org/10.1186/s13073-014-0123-1 Text en © Bradner; licensee BioMed Central Ltd. 2014 The licensee has exclusive rights to distribute this article, in any medium, for 12 months following its publication. After this time, the article is available under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| spellingShingle | Q and A Bradner, James E From transcriptional regulation to drugging the cancer epigenome |
| title | From transcriptional regulation to drugging the cancer epigenome |
| title_full | From transcriptional regulation to drugging the cancer epigenome |
| title_fullStr | From transcriptional regulation to drugging the cancer epigenome |
| title_full_unstemmed | From transcriptional regulation to drugging the cancer epigenome |
| title_short | From transcriptional regulation to drugging the cancer epigenome |
| title_sort | from transcriptional regulation to drugging the cancer epigenome |
| topic | Q and A |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295578/ https://www.ncbi.nlm.nih.gov/pubmed/25593599 http://dx.doi.org/10.1186/s13073-014-0123-1 |
| work_keys_str_mv | AT bradnerjamese fromtranscriptionalregulationtodruggingthecancerepigenome |