Cargando…

Synthesis and Structural Activity Relationship Study of Antitubercular Carboxamides

The unusual structure and chemical composition of the mycobacterial cell wall, the tedious duration of therapy, and resistance developed by the microorganism have made the recurrence of the disease multidrug resistance and extensive or extreme drug resistance. The prevalence of tuberculosis in syner...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ugwu, D. I., Ezema, B. E., Eze, F. U., Ugwuja, D. I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295614/ https://www.ncbi.nlm.nih.gov/pubmed/25610646 http://dx.doi.org/10.1155/2014/614808

Ejemplares similares

Discovery and Structure–Activity-Relationship Study of N-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-β-d-ribose 2′-Oxidase
por: Oh, Sangmi, et al.
Publicado: (2018)

New carboxamide derivatives bearing benzenesulphonamide as a selective COX-II inhibitor: Design, synthesis and structure-activity relationship
por: Ugwu, David Izuchukwu, et al.
Publicado: (2017)

Antitubercular 2-Pyrazolylpyrimidinones: Structure–Activity Relationship and Mode-of-Action Studies
por: Soares de Melo, Candice, et al.
Publicado: (2021)

Synthesis and Structure–Activity Relationships of a New Class of Oxadiazoles Targeting DprE1 as Antitubercular Agents
por: Yadav, Veena D., et al.
Publicado: (2023)

Novel Antitubercular 6-Dialkylaminopyrimidine Carboxamides from Phenotypic Whole-Cell High Throughput Screening of a SoftFocus Library: Structure–Activity Relationship and Target Identification Studies
por: Wilson, Colin R., et al.
Publicado: (2017)

Synthesis, characterization and in vitro antitrypanosomal activities of new carboxamides bearing quinoline moiety
por: Ugwu, David Izuchukwu, et al.
Publicado: (2018)

Cinnamic Derivatives as Antitubercular Agents: Characterization by Quantitative Structure–Activity Relationship Studies
por: Teixeira, Cátia, et al.
Publicado: (2020)

Plumbagin analogs-synthesis, characterization, and antitubercular activity
por: Nayak, Nishi, et al.
Publicado: (2014)

Synthesis and structure−activity relationship of 8-substituted protoberberine derivatives as a novel class of antitubercular agents
por: Li, Ying-Hong, et al.
Publicado: (2013)

New Quinoline–Urea–Benzothiazole Hybrids as Promising Antitubercular Agents: Synthesis, In Vitro Antitubercular Activity, Cytotoxicity Studies, and In Silico ADME Profiling
por: Moodley, Rashmika, et al.
Publicado: (2022)

New chalcone derivatives as potential antimicrobial and antioxidant agent
por: Okolo, Emelda N., et al.
Publicado: (2021)

New peptide derived antimalaria and antimicrobial agents bearing sulphonamide moiety
por: Ugwuja, D. I., et al.
Publicado: (2019)

Synthesis, Antitubercular Activity and Mechanism of Resistance of Highly Effective Thiacetazone Analogues
por: Coxon, Geoffrey D., et al.
Publicado: (2013)

Design, Synthesis and Antitubercular Activity of Certain Nicotinic Acid Hydrazides
por: Eldehna, Wagdy M., et al.
Publicado: (2015)

Antibacterial and Antitubercular Activities of Cinnamylideneacetophenones
por: Polaquini, Carlos R., et al.
Publicado: (2017)

Structure–Activity Relationships of Pyrazolo[1,5-a]pyrimidin-7(4H)-ones as Antitubercular Agents
por: Oh, Sangmi, et al.
Publicado: (2021)

Impact of the host environment on the antitubercular action of pyrazinamide
por: Lamont, Elise A., et al.
Publicado: (2019)

Antioxidant, Antitubercular and Cytotoxic Activities of Piper imperiale
por: Diaz, Luis E., et al.
Publicado: (2012)

Semi-Synthesis of Marine-Derived Ilamycin F Derivatives and Their Antitubercular Activities
por: Li, Jun, et al.
Publicado: (2021)

Structure–Activity Relationship Studies of Pyrimidine-4-Carboxamides as Inhibitors of N-Acylphosphatidylethanolamine Phospholipase D
por: Mock, Elliot D., et al.
Publicado: (2020)

Antitubercular Nitroimidazoles Revisited: Synthesis and Activity of the Authentic 3-Nitro Isomer of Pretomanid
por: Thompson, Andrew M., et al.
Publicado: (2017)

Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity
por: Oliveira, Paulo F. M., et al.
Publicado: (2017)

Synthesis and Antitubercular Activity of Heteroaromatic Isonicotinoyl and 7-Chloro-4-Quinolinyl Hydrazone Derivatives
por: Ferreira, Marcelle de L., et al.
Publicado: (2010)

The Synthesis and Anti-Cytomegalovirus Activity of Piperidine-4-Carboxamides
por: Guo, Xin, et al.
Publicado: (2022)

Byrsonima fagifolia Niedenzu Apolar Compounds with Antitubercular Activity
por: Higuchi, C. T., et al.
Publicado: (2011)

Pyrrolyl Pyrazoline Carbaldehydes as Enoyl-ACP Reductase Inhibitors: Design, Synthesis and Antitubercular Activity
por: Dixit, Sheshagiri R., et al.
Publicado: (2017)

Application of Lipid-Based Nanocarriers for Antitubercular Drug Delivery: A Review
por: Buya, Aristote B., et al.
Publicado: (2021)

Design, Synthesis and Evaluation of Antitubercular Activity of Novel Dihydropyridine Containing Imidazolyl Substituent
por: Iman, Maryam, et al.
Publicado: (2015)

Design and Synthesis of Some Novel Fluorobenzimidazoles Substituted with Structural Motifs Present in Physiologically Active Natural Products for Antitubercular Activity
por: Nandha, Bangalore, et al.
Publicado: (2017)

Deciphering the mechanism of action of antitubercular compounds with metabolomics
por: Sakallioglu, Isin T., et al.
Publicado: (2021)

8-cyanobenzothiazinone analogs with potent antitubercular activity
por: Zhang, Gang, et al.
Publicado: (2021)

Design, Synthesis, and Characterization of N-Oxide-Containing Heterocycles with in Vivo Sterilizing Antitubercular Activity
por: dos Santos Fernandes, Guilherme Felipe, et al.
Publicado: (2017)

Design, Synthesis, and Biological Evaluation of 2-Nitroimidazopyrazin-one/-es with Antitubercular and Antiparasitic Activity
por: Jarrad, Angie M., et al.
Publicado: (2018)

Conventional and Microwave-Assisted Synthesis, Antitubercular Activity, and Molecular Docking Studies of Pyrazole and Oxadiazole Hybrids
por: Desai, Nisheeth C., et al.
Publicado: (2021)

Synthesis, Characterization, Antitubercular Activity, and Molecular Docking Studies of Pyrazolylpyrazoline-Clubbed Triazole and Tetrazole Hybrids
por: Zala, Mayursinh, et al.
Publicado: (2023)

N′-Substituted 4-Phenylpicolinohydrazonamides with Thiosemicarbazone Moiety as New Potential Antitubercular Agents: Synthesis, Structure and Evaluation of Antimicrobial Activity
por: Gobis, Katarzyna, et al.
Publicado: (2022)

Design, Synthesis and Antitubercular Evaluation of Novel Series of Pyrazinecarboxamide Metal Complexes
por: Ali, Mohsin, et al.
Publicado: (2018)

Rational design and synthesis of novel diphenyl ether derivatives as antitubercular agents
por: Kar, Sidhartha S, et al.
Publicado: (2016)

Design, synthesis, antitubercular and antiviral properties of new spirocyclic indole derivatives
por: Cihan-Üstündağ, Gökçe, et al.
Publicado: (2019)

Synthesis and antibacterial activity of monocyclic 3-carboxamide tetramic acids
por: Jeong, Yong-Chul, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_uljeaplfb0bkhr0e2isupm8sod