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Single-Chain Semiconducting Polymer Dots

[Image: see text] This work describes the preparation and validation of single-chain semiconducting polymer dots (sPdots), which were generated using a method based on surface immobilization, washing, and cleavage. The sPdots have an ultrasmall size of ∼3.0 nm as determined by atomic force microscop...

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Detalles Bibliográficos
Autores principales: Ye, Fangmao, Sun, Wei, Zhang, Yue, Wu, Changfeng, Zhang, Xuanjun, Yu, Jiangbo, Rong, Yu, Zhang, Miqin, Chiu, Daniel T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295807/
https://www.ncbi.nlm.nih.gov/pubmed/25521606
http://dx.doi.org/10.1021/la5038684
Descripción
Sumario:[Image: see text] This work describes the preparation and validation of single-chain semiconducting polymer dots (sPdots), which were generated using a method based on surface immobilization, washing, and cleavage. The sPdots have an ultrasmall size of ∼3.0 nm as determined by atomic force microscopy, a size that is consistent with the anticipated diameter calculated from the molecular weight of the single-chain semiconducting polymer. sPdots should find use in biology and medicine as a new class of fluorescent probes. The FRET assay this work presents is a simple and rapid test to ensure methods developed for preparing sPdot indeed produced single-chain Pdots as designed.