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Impact of Polymer Conformation on the Crystal Growth Inhibition of a Poorly Water-Soluble Drug in Aqueous Solution

[Image: see text] Poor aqueous solubility is a major hindrance to oral delivery of many emerging drugs. Supersaturated drug solutions can improve passive absorption across the gastrointestinal tract membrane as long as crystallization can be inhibited, enhancing the delivery of such poorly soluble t...

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Detalles Bibliográficos
Autores principales: Schram, Caitlin J., Beaudoin, Stephen P., Taylor, Lynne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295812/
https://www.ncbi.nlm.nih.gov/pubmed/25486041
http://dx.doi.org/10.1021/la503644m