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Promiscuous RNA Binding Ensures Effective Encapsidation of APOBEC3 Proteins by HIV-1

The apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3) proteins are cell-encoded cytidine deaminases, some of which, such as APOBEC3G (A3G) and APOBEC3F (A3F), act as potent human immunodeficiency virus type-1 (HIV-1) restriction factors. These proteins require packaging int...

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Detalles Bibliográficos
Autores principales: Apolonia, Luis, Schulz, Reiner, Curk, Tomaž, Rocha, Paula, Swanson, Chad M., Schaller, Torsten, Ule, Jernej, Malim, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295846/
https://www.ncbi.nlm.nih.gov/pubmed/25590131
http://dx.doi.org/10.1371/journal.ppat.1004609