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Targeting Therapy to The Neuromuscular Junction: Proof of Concept

INTRODUCTION: The site of pathology in myasthenia gravis (MG) is the neuromuscular junction (NMJ). Our goal was to determine the ability to direct complement inhibition to the NMJ. Methods: A single-chain antibody directed against the alpha subunit of the acetylcholine receptor was synthesized (scFv...

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Detalles Bibliográficos
Autores principales:	Kusner, Linda L, Satija, Namita, Cheng, Georgiana, Kaminski, Henry J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Main Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296224/ https://www.ncbi.nlm.nih.gov/pubmed/24037951 http://dx.doi.org/10.1002/mus.24057

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