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Segmental Quantitative MR Imaging Analysis of Diurnal Variation of Water Content in the Lumbar Intervertebral Discs

OBJECTIVE: To investigate the changes in water content in the lumbar intervertebral discs by quantitative T2 MR imaging in the morning after bed rest and evening after a diurnal load. MATERIALS AND METHODS: Twenty healthy volunteers were separately examined in the morning after bed rest and in the e...

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Autores principales: Zhu, Tingting, Ai, Tao, Zhang, Wei, Li, Tao, Li, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Radiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296262/
https://www.ncbi.nlm.nih.gov/pubmed/25598682
http://dx.doi.org/10.3348/kjr.2015.16.1.139
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author Zhu, Tingting
Ai, Tao
Zhang, Wei
Li, Tao
Li, Xiaoming
author_facet Zhu, Tingting
Ai, Tao
Zhang, Wei
Li, Tao
Li, Xiaoming
author_sort Zhu, Tingting
collection PubMed
description OBJECTIVE: To investigate the changes in water content in the lumbar intervertebral discs by quantitative T2 MR imaging in the morning after bed rest and evening after a diurnal load. MATERIALS AND METHODS: Twenty healthy volunteers were separately examined in the morning after bed rest and in the evening after finishing daily work. T2-mapping images were obtained and analyzed. An equally-sized rectangular region of interest (ROI) was manually placed in both, the anterior and the posterior annulus fibrosus (AF), in the outermost 20% of the disc. Three ROIs were placed in the space defined as the nucleus pulposus (NP). Repeated-measures analysis of variance and paired 2-tailed t tests were used for statistical analysis, with p < 0.05 as significantly different. RESULTS: T2 values significantly decreased from morning to evening, in the NP (anterior NP = -13.9 ms; central NP = -17.0 ms; posterior NP = -13.3 ms; all p < 0.001). Meanwhile T2 values significantly increased in the anterior AF (+2.9 ms; p = 0.025) and the posterior AF (+5.9 ms; p < 0.001). T2 values in the posterior AF showed the largest degree of variation among the 5 ROIs, but there was no statistical significance (p = 0.414). Discs with initially low T2 values in the center NP showed a smaller degree of variation in the anterior NP and in the central NP, than in discs with initially high T2 values in the center NP (10.0% vs. 16.1%, p = 0.037; 6.4% vs. 16.1%, p = 0.006, respectively). CONCLUSION: Segmental quantitative T2 MRI provides valuable insights into physiological aspects of normal discs.
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spelling pubmed-42962622015-01-16 Segmental Quantitative MR Imaging Analysis of Diurnal Variation of Water Content in the Lumbar Intervertebral Discs Zhu, Tingting Ai, Tao Zhang, Wei Li, Tao Li, Xiaoming Korean J Radiol Musculoskeletal Imaging OBJECTIVE: To investigate the changes in water content in the lumbar intervertebral discs by quantitative T2 MR imaging in the morning after bed rest and evening after a diurnal load. MATERIALS AND METHODS: Twenty healthy volunteers were separately examined in the morning after bed rest and in the evening after finishing daily work. T2-mapping images were obtained and analyzed. An equally-sized rectangular region of interest (ROI) was manually placed in both, the anterior and the posterior annulus fibrosus (AF), in the outermost 20% of the disc. Three ROIs were placed in the space defined as the nucleus pulposus (NP). Repeated-measures analysis of variance and paired 2-tailed t tests were used for statistical analysis, with p < 0.05 as significantly different. RESULTS: T2 values significantly decreased from morning to evening, in the NP (anterior NP = -13.9 ms; central NP = -17.0 ms; posterior NP = -13.3 ms; all p < 0.001). Meanwhile T2 values significantly increased in the anterior AF (+2.9 ms; p = 0.025) and the posterior AF (+5.9 ms; p < 0.001). T2 values in the posterior AF showed the largest degree of variation among the 5 ROIs, but there was no statistical significance (p = 0.414). Discs with initially low T2 values in the center NP showed a smaller degree of variation in the anterior NP and in the central NP, than in discs with initially high T2 values in the center NP (10.0% vs. 16.1%, p = 0.037; 6.4% vs. 16.1%, p = 0.006, respectively). CONCLUSION: Segmental quantitative T2 MRI provides valuable insights into physiological aspects of normal discs. The Korean Society of Radiology 2015 2015-01-09 /pmc/articles/PMC4296262/ /pubmed/25598682 http://dx.doi.org/10.3348/kjr.2015.16.1.139 Text en Copyright © 2015 The Korean Society of Radiology http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Musculoskeletal Imaging
Zhu, Tingting
Ai, Tao
Zhang, Wei
Li, Tao
Li, Xiaoming
Segmental Quantitative MR Imaging Analysis of Diurnal Variation of Water Content in the Lumbar Intervertebral Discs
title Segmental Quantitative MR Imaging Analysis of Diurnal Variation of Water Content in the Lumbar Intervertebral Discs
title_full Segmental Quantitative MR Imaging Analysis of Diurnal Variation of Water Content in the Lumbar Intervertebral Discs
title_fullStr Segmental Quantitative MR Imaging Analysis of Diurnal Variation of Water Content in the Lumbar Intervertebral Discs
title_full_unstemmed Segmental Quantitative MR Imaging Analysis of Diurnal Variation of Water Content in the Lumbar Intervertebral Discs
title_short Segmental Quantitative MR Imaging Analysis of Diurnal Variation of Water Content in the Lumbar Intervertebral Discs
title_sort segmental quantitative mr imaging analysis of diurnal variation of water content in the lumbar intervertebral discs
topic Musculoskeletal Imaging
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296262/
https://www.ncbi.nlm.nih.gov/pubmed/25598682
http://dx.doi.org/10.3348/kjr.2015.16.1.139
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