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Integrin alpha L controls the homing of regulatory T cells during CNS autoimmunity in the absence of integrin alpha 4

Experimental autoimmune encephalomyelitis (EAE), the animal model of multiple sclerosis (MS), results from an autoimmune attack of the central nervous system (CNS) by effector T helper (Th) 1 and Th17 cells. Regulatory T cells (Treg) can control effector T cells and limit the progression of CNS auto...

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Detalles Bibliográficos
Autores principales: Glatigny, Simon, Duhen, Rebekka, Arbelaez, Carlos, Kumari, Swarnima, Bettelli, Estelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296287/
https://www.ncbi.nlm.nih.gov/pubmed/25592296
http://dx.doi.org/10.1038/srep07834