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A novel IgM–H-Ficolin complement pathway to attack allogenic cancer cells in vitro
The pentameric serum IgMs are critical to immune defense and surveillance through cytotoxicity against microbes and nascent cancer cells. Ficolins, a group of oligomeric lectins with an overall structure similar to C1q and mannose-binding lectin (MBL) participate in microbe infection and apoptotic c...
Autores principales: | Lei, Xiaoying, Liu, Chaoxu, Azadzoi, Kazem, Li, Cuiling, Lu, Fan, Xiang, An, Sun, Jianbin, Guo, Yanhai, Zhao, Qingchuan, Yan, Zhen, Yang, Jinghua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296296/ https://www.ncbi.nlm.nih.gov/pubmed/25592840 http://dx.doi.org/10.1038/srep07824 |
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