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Efficacy of hyaluronic acid (hyaluronan) in root coverage procedures as an adjunct to coronally advanced flap in Millers Class I recession: A clinical study

BACKGROUND: The purpose of this study was to assess the efficacy of hyaluronic acid (HA) in root coverage procedures as an adjunct to coronally advanced flap (CAF) procedure. MATERIALS AND METHODS: This was a randomized clinical trial with split mouth design, where 10 patients with 20 sites of Mille...

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Autores principales: Kumar, Radhika, Srinivas, Moogala, Pai, Jagdish, Suragimath, Girish, Prasad, Krishna, Polepalle, Tejaswin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296460/
https://www.ncbi.nlm.nih.gov/pubmed/25624632
http://dx.doi.org/10.4103/0972-124X.147411
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author Kumar, Radhika
Srinivas, Moogala
Pai, Jagdish
Suragimath, Girish
Prasad, Krishna
Polepalle, Tejaswin
author_facet Kumar, Radhika
Srinivas, Moogala
Pai, Jagdish
Suragimath, Girish
Prasad, Krishna
Polepalle, Tejaswin
author_sort Kumar, Radhika
collection PubMed
description BACKGROUND: The purpose of this study was to assess the efficacy of hyaluronic acid (HA) in root coverage procedures as an adjunct to coronally advanced flap (CAF) procedure. MATERIALS AND METHODS: This was a randomized clinical trial with split mouth design, where 10 patients with 20 sites of Millers Class I recession were treated and followed-up for a period of 6 months. CAF procedure was performed, HA was applied onto the experimental sites before suturing the flap. Recession depth (RD) was measured regularly at baseline 1, 3, 6, 12, and 24 weeks postoperatively. Probing pocket depth (PPD) and clinical attachment level (CAL) were also measured along with RD at baseline and 12 and 24 weeks. RESULTS: There was a significant change in RD, PPD, CAL, and percentage of root coverage in both groups when compared to the baseline values. There was no statistically significant difference between experimental and control group in terms of RD (P = 0.917), PPD (P = 0.917) and CAL (P = 0.761). RD was 3.2 mm ± 0.78 mm in experimental site and control sites 2.9 mm ± 0.73 mm reduced to 1.1 mm ± 0.99 mm in experimental sites and 1.0 mm ± 0.66 mm in control sites. Though, there is no statistically significant difference root coverage in the experimental group appeared to be clinically more stable compared with the control group after 24 weeks. CONCLUSIONS: This study suggests that use of HA may improve the clinical outcome of root coverage with CAF procedure.
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spelling pubmed-42964602015-01-26 Efficacy of hyaluronic acid (hyaluronan) in root coverage procedures as an adjunct to coronally advanced flap in Millers Class I recession: A clinical study Kumar, Radhika Srinivas, Moogala Pai, Jagdish Suragimath, Girish Prasad, Krishna Polepalle, Tejaswin J Indian Soc Periodontol Original Article BACKGROUND: The purpose of this study was to assess the efficacy of hyaluronic acid (HA) in root coverage procedures as an adjunct to coronally advanced flap (CAF) procedure. MATERIALS AND METHODS: This was a randomized clinical trial with split mouth design, where 10 patients with 20 sites of Millers Class I recession were treated and followed-up for a period of 6 months. CAF procedure was performed, HA was applied onto the experimental sites before suturing the flap. Recession depth (RD) was measured regularly at baseline 1, 3, 6, 12, and 24 weeks postoperatively. Probing pocket depth (PPD) and clinical attachment level (CAL) were also measured along with RD at baseline and 12 and 24 weeks. RESULTS: There was a significant change in RD, PPD, CAL, and percentage of root coverage in both groups when compared to the baseline values. There was no statistically significant difference between experimental and control group in terms of RD (P = 0.917), PPD (P = 0.917) and CAL (P = 0.761). RD was 3.2 mm ± 0.78 mm in experimental site and control sites 2.9 mm ± 0.73 mm reduced to 1.1 mm ± 0.99 mm in experimental sites and 1.0 mm ± 0.66 mm in control sites. Though, there is no statistically significant difference root coverage in the experimental group appeared to be clinically more stable compared with the control group after 24 weeks. CONCLUSIONS: This study suggests that use of HA may improve the clinical outcome of root coverage with CAF procedure. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4296460/ /pubmed/25624632 http://dx.doi.org/10.4103/0972-124X.147411 Text en Copyright: © Journal of Indian Society of Periodontology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kumar, Radhika
Srinivas, Moogala
Pai, Jagdish
Suragimath, Girish
Prasad, Krishna
Polepalle, Tejaswin
Efficacy of hyaluronic acid (hyaluronan) in root coverage procedures as an adjunct to coronally advanced flap in Millers Class I recession: A clinical study
title Efficacy of hyaluronic acid (hyaluronan) in root coverage procedures as an adjunct to coronally advanced flap in Millers Class I recession: A clinical study
title_full Efficacy of hyaluronic acid (hyaluronan) in root coverage procedures as an adjunct to coronally advanced flap in Millers Class I recession: A clinical study
title_fullStr Efficacy of hyaluronic acid (hyaluronan) in root coverage procedures as an adjunct to coronally advanced flap in Millers Class I recession: A clinical study
title_full_unstemmed Efficacy of hyaluronic acid (hyaluronan) in root coverage procedures as an adjunct to coronally advanced flap in Millers Class I recession: A clinical study
title_short Efficacy of hyaluronic acid (hyaluronan) in root coverage procedures as an adjunct to coronally advanced flap in Millers Class I recession: A clinical study
title_sort efficacy of hyaluronic acid (hyaluronan) in root coverage procedures as an adjunct to coronally advanced flap in millers class i recession: a clinical study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296460/
https://www.ncbi.nlm.nih.gov/pubmed/25624632
http://dx.doi.org/10.4103/0972-124X.147411
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