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Mutational profiles of different macroscopic subtypes of colorectal adenoma reveal distinct pathogenetic roles for KRAS, BRAF and PIK3CA

BACKGROUND: Investigations of genetic alterations and correlations with histology or morphology could provide further insights into colorectal carcinogenesis. Nevertheless, such genetic changes were less investigated in adenoma stage and a comprehensive survey of oncogenic mutations in EGFR signalin...

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Detalles Bibliográficos
Autores principales:	Chang, Li-Chun, Chiu, Han-Mo, Shun, Chia-Tung, Liang, Jin-Tung, Lin, Jaw-Town, Chen, Chien-Chuan, Lee, Yi-Chia, Wu, Ming-Shiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296683/ https://www.ncbi.nlm.nih.gov/pubmed/25551625 http://dx.doi.org/10.1186/s12876-014-0221-y

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