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Bilateral Internal Auditory Canal Metastasis of Non-small Cell Lung Cancer
We report on a patient with brain metastasis involving bilateral internal auditory canal from non-small cell lung cancer (NSCLC). A 49-year-old woman who had been diagnosed with NSCLC (T2aN1M0) complained of persistent vertigo and bilateral tinnitus for three months. The patient had refused all trea...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Cancer Association
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296856/ https://www.ncbi.nlm.nih.gov/pubmed/25381831 http://dx.doi.org/10.4143/crt.2013.079 |
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author | Kim, Chang-Hee Shin, Jung Eun Kim, Hee Joung Lee, Kye Young |
author_facet | Kim, Chang-Hee Shin, Jung Eun Kim, Hee Joung Lee, Kye Young |
author_sort | Kim, Chang-Hee |
collection | PubMed |
description | We report on a patient with brain metastasis involving bilateral internal auditory canal from non-small cell lung cancer (NSCLC). A 49-year-old woman who had been diagnosed with NSCLC (T2aN1M0) complained of persistent vertigo and bilateral tinnitus for three months. The patient had refused all treatments, including surgery and chemotherapy; however, she sought alternative medicine. The patient’s hearing loss showed rapid progression bilaterally, and rotatory vertigo with peripheral-type nystagmus developed. Magnetic resonance imaging of the brain showed irregular nodular enhancement within both internal auditory canals with leptomeningeal enhancement and multiple intracranial metastasis. The patient was treated with epidermal growth factor receptor-tyrosine kinase inhibitor, and the tumor showed partial response. This was a rare case of multiple brain metastases involving bilateral internal auditory canal from known NSCLC presenting with vertigo and hearing loss. |
format | Online Article Text |
id | pubmed-4296856 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Korean Cancer Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-42968562015-01-20 Bilateral Internal Auditory Canal Metastasis of Non-small Cell Lung Cancer Kim, Chang-Hee Shin, Jung Eun Kim, Hee Joung Lee, Kye Young Cancer Res Treat Case Report We report on a patient with brain metastasis involving bilateral internal auditory canal from non-small cell lung cancer (NSCLC). A 49-year-old woman who had been diagnosed with NSCLC (T2aN1M0) complained of persistent vertigo and bilateral tinnitus for three months. The patient had refused all treatments, including surgery and chemotherapy; however, she sought alternative medicine. The patient’s hearing loss showed rapid progression bilaterally, and rotatory vertigo with peripheral-type nystagmus developed. Magnetic resonance imaging of the brain showed irregular nodular enhancement within both internal auditory canals with leptomeningeal enhancement and multiple intracranial metastasis. The patient was treated with epidermal growth factor receptor-tyrosine kinase inhibitor, and the tumor showed partial response. This was a rare case of multiple brain metastases involving bilateral internal auditory canal from known NSCLC presenting with vertigo and hearing loss. Korean Cancer Association 2015-01 2014-08-28 /pmc/articles/PMC4296856/ /pubmed/25381831 http://dx.doi.org/10.4143/crt.2013.079 Text en Copyright © 2015 by the Korean Cancer Association This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Kim, Chang-Hee Shin, Jung Eun Kim, Hee Joung Lee, Kye Young Bilateral Internal Auditory Canal Metastasis of Non-small Cell Lung Cancer |
title | Bilateral Internal Auditory Canal Metastasis of Non-small Cell Lung Cancer |
title_full | Bilateral Internal Auditory Canal Metastasis of Non-small Cell Lung Cancer |
title_fullStr | Bilateral Internal Auditory Canal Metastasis of Non-small Cell Lung Cancer |
title_full_unstemmed | Bilateral Internal Auditory Canal Metastasis of Non-small Cell Lung Cancer |
title_short | Bilateral Internal Auditory Canal Metastasis of Non-small Cell Lung Cancer |
title_sort | bilateral internal auditory canal metastasis of non-small cell lung cancer |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296856/ https://www.ncbi.nlm.nih.gov/pubmed/25381831 http://dx.doi.org/10.4143/crt.2013.079 |
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