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Bilateral Internal Auditory Canal Metastasis of Non-small Cell Lung Cancer

We report on a patient with brain metastasis involving bilateral internal auditory canal from non-small cell lung cancer (NSCLC). A 49-year-old woman who had been diagnosed with NSCLC (T2aN1M0) complained of persistent vertigo and bilateral tinnitus for three months. The patient had refused all trea...

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Autores principales: Kim, Chang-Hee, Shin, Jung Eun, Kim, Hee Joung, Lee, Kye Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296856/
https://www.ncbi.nlm.nih.gov/pubmed/25381831
http://dx.doi.org/10.4143/crt.2013.079
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author Kim, Chang-Hee
Shin, Jung Eun
Kim, Hee Joung
Lee, Kye Young
author_facet Kim, Chang-Hee
Shin, Jung Eun
Kim, Hee Joung
Lee, Kye Young
author_sort Kim, Chang-Hee
collection PubMed
description We report on a patient with brain metastasis involving bilateral internal auditory canal from non-small cell lung cancer (NSCLC). A 49-year-old woman who had been diagnosed with NSCLC (T2aN1M0) complained of persistent vertigo and bilateral tinnitus for three months. The patient had refused all treatments, including surgery and chemotherapy; however, she sought alternative medicine. The patient’s hearing loss showed rapid progression bilaterally, and rotatory vertigo with peripheral-type nystagmus developed. Magnetic resonance imaging of the brain showed irregular nodular enhancement within both internal auditory canals with leptomeningeal enhancement and multiple intracranial metastasis. The patient was treated with epidermal growth factor receptor-tyrosine kinase inhibitor, and the tumor showed partial response. This was a rare case of multiple brain metastases involving bilateral internal auditory canal from known NSCLC presenting with vertigo and hearing loss.
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spelling pubmed-42968562015-01-20 Bilateral Internal Auditory Canal Metastasis of Non-small Cell Lung Cancer Kim, Chang-Hee Shin, Jung Eun Kim, Hee Joung Lee, Kye Young Cancer Res Treat Case Report We report on a patient with brain metastasis involving bilateral internal auditory canal from non-small cell lung cancer (NSCLC). A 49-year-old woman who had been diagnosed with NSCLC (T2aN1M0) complained of persistent vertigo and bilateral tinnitus for three months. The patient had refused all treatments, including surgery and chemotherapy; however, she sought alternative medicine. The patient’s hearing loss showed rapid progression bilaterally, and rotatory vertigo with peripheral-type nystagmus developed. Magnetic resonance imaging of the brain showed irregular nodular enhancement within both internal auditory canals with leptomeningeal enhancement and multiple intracranial metastasis. The patient was treated with epidermal growth factor receptor-tyrosine kinase inhibitor, and the tumor showed partial response. This was a rare case of multiple brain metastases involving bilateral internal auditory canal from known NSCLC presenting with vertigo and hearing loss. Korean Cancer Association 2015-01 2014-08-28 /pmc/articles/PMC4296856/ /pubmed/25381831 http://dx.doi.org/10.4143/crt.2013.079 Text en Copyright © 2015 by the Korean Cancer Association This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kim, Chang-Hee
Shin, Jung Eun
Kim, Hee Joung
Lee, Kye Young
Bilateral Internal Auditory Canal Metastasis of Non-small Cell Lung Cancer
title Bilateral Internal Auditory Canal Metastasis of Non-small Cell Lung Cancer
title_full Bilateral Internal Auditory Canal Metastasis of Non-small Cell Lung Cancer
title_fullStr Bilateral Internal Auditory Canal Metastasis of Non-small Cell Lung Cancer
title_full_unstemmed Bilateral Internal Auditory Canal Metastasis of Non-small Cell Lung Cancer
title_short Bilateral Internal Auditory Canal Metastasis of Non-small Cell Lung Cancer
title_sort bilateral internal auditory canal metastasis of non-small cell lung cancer
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296856/
https://www.ncbi.nlm.nih.gov/pubmed/25381831
http://dx.doi.org/10.4143/crt.2013.079
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