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TGF-β Suppresses COX-2 Expression by Tristetraprolin-Mediated RNA Destabilization in A549 Human Lung Cancer Cells
PURPOSE: Overexpression of cyclooxygenase 2 (COX-2) is thought to promote survival of transformed cells. Transforming growth factor β (TGF-β) exerts anti-proliferative effects on a broad range of epithelial cells. In the current study, we investigated whether TGF-β can regulate COX-2 expression in A...
Autores principales: | Kang, Soyeong, Min, Ahrum, Im, Seock-Ah, Song, Sang-Hyun, Kim, Sang Gyun, Kim, Hyun-Ah, Kim, Hee-Jun, Oh, Do-Youn, Jong, Hyun-Soon, Kim, Tae-You, Bang, Yung-Jue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Cancer Association
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296860/ https://www.ncbi.nlm.nih.gov/pubmed/25544576 http://dx.doi.org/10.4143/crt.2013.192 |
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