CHK2 kinase in the DNA damage response and beyond

The serine/threonine kinase CHK2 is a key component of the DNA damage response. In human cells, following genotoxic stress, CHK2 is activated and phosphorylates >20 proteins to induce the appropriate cellular response, which, depending on the extent of damage, the cell type, and other factors, co...

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Detalles Bibliográficos
Autores principales: Zannini, Laura, Delia, Domenico, Buscemi, Giacomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296918/
https://www.ncbi.nlm.nih.gov/pubmed/25404613
http://dx.doi.org/10.1093/jmcb/mju045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296918/
https://www.ncbi.nlm.nih.gov/pubmed/25404613
http://dx.doi.org/10.1093/jmcb/mju045

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