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CHK2 kinase in the DNA damage response and beyond

The serine/threonine kinase CHK2 is a key component of the DNA damage response. In human cells, following genotoxic stress, CHK2 is activated and phosphorylates >20 proteins to induce the appropriate cellular response, which, depending on the extent of damage, the cell type, and other factors, co...

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Detalles Bibliográficos
Autores principales:	Zannini, Laura, Delia, Domenico, Buscemi, Giacomo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296918/ https://www.ncbi.nlm.nih.gov/pubmed/25404613 http://dx.doi.org/10.1093/jmcb/mju045

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