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Bone-Induced Chondroinduction in Sheep Jamshidi Biopsy Defects with and without Treatment by Subchondral Chitosan-Blood Implant: 1-Day, 3-Week, and 3-Month Repair

OBJECTIVE: Delivery of chitosan to subchondral bone is a novel approach for augmented marrow stimulation. We evaluated the effect of 3 presolidified chitosan-blood implant formulations on osteochondral repair progression compared with untreated defects. DESIGN: In N = 5 adult sheep, six 2-mm diamete...

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Detalles Bibliográficos
Autores principales: Bell, Angela D., Lascau-Coman, Viorica, Sun, Jun, Chen, Gaoping, Lowerison, Mark W., Hurtig, Mark B., Hoemann, Caroline D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297102/
https://www.ncbi.nlm.nih.gov/pubmed/26069656
http://dx.doi.org/10.1177/1947603512463227