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Supporting Biomaterials for Articular Cartilage Repair
Orthopedic surgeons and researchers worldwide are continuously faced with the challenge of regenerating articular cartilage defects. However, until now, it has not been possible to completely mimic the biological and biochemical properties of articular cartilage using current research and developmen...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297118/ https://www.ncbi.nlm.nih.gov/pubmed/26069634 http://dx.doi.org/10.1177/1947603512444722 |
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author | Duarte Campos, Daniela Filipa Drescher, Wolf Rath, Björn Tingart, Markus Fischer, Horst |
author_facet | Duarte Campos, Daniela Filipa Drescher, Wolf Rath, Björn Tingart, Markus Fischer, Horst |
author_sort | Duarte Campos, Daniela Filipa |
collection | PubMed |
description | Orthopedic surgeons and researchers worldwide are continuously faced with the challenge of regenerating articular cartilage defects. However, until now, it has not been possible to completely mimic the biological and biochemical properties of articular cartilage using current research and development approaches. In this review, biomaterials previously used for articular cartilage repair research are addressed. Furthermore, a brief discussion of the state of the art of current cell printing procedures mimicking native cartilage is offered in light of their use as future alternatives for cartilage tissue engineering. Inkjet cell printing, controlled deposition cell printing tools, and laser cell printing are cutting-edge techniques in this context. The development of mimetic hydrogels with specific biological properties relevant to articular cartilage native tissue will support the development of improved, functional, and novel engineered tissue for clinical application. |
format | Online Article Text |
id | pubmed-4297118 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-42971182015-06-11 Supporting Biomaterials for Articular Cartilage Repair Duarte Campos, Daniela Filipa Drescher, Wolf Rath, Björn Tingart, Markus Fischer, Horst Cartilage Review Orthopedic surgeons and researchers worldwide are continuously faced with the challenge of regenerating articular cartilage defects. However, until now, it has not been possible to completely mimic the biological and biochemical properties of articular cartilage using current research and development approaches. In this review, biomaterials previously used for articular cartilage repair research are addressed. Furthermore, a brief discussion of the state of the art of current cell printing procedures mimicking native cartilage is offered in light of their use as future alternatives for cartilage tissue engineering. Inkjet cell printing, controlled deposition cell printing tools, and laser cell printing are cutting-edge techniques in this context. The development of mimetic hydrogels with specific biological properties relevant to articular cartilage native tissue will support the development of improved, functional, and novel engineered tissue for clinical application. SAGE Publications 2012-07 /pmc/articles/PMC4297118/ /pubmed/26069634 http://dx.doi.org/10.1177/1947603512444722 Text en © The Author(s) 2012 |
spellingShingle | Review Duarte Campos, Daniela Filipa Drescher, Wolf Rath, Björn Tingart, Markus Fischer, Horst Supporting Biomaterials for Articular Cartilage Repair |
title | Supporting Biomaterials for Articular Cartilage Repair |
title_full | Supporting Biomaterials for Articular Cartilage Repair |
title_fullStr | Supporting Biomaterials for Articular Cartilage Repair |
title_full_unstemmed | Supporting Biomaterials for Articular Cartilage Repair |
title_short | Supporting Biomaterials for Articular Cartilage Repair |
title_sort | supporting biomaterials for articular cartilage repair |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297118/ https://www.ncbi.nlm.nih.gov/pubmed/26069634 http://dx.doi.org/10.1177/1947603512444722 |
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