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Unique features of apicoplast DNA gyrases from Toxoplasma gondii and Plasmodium falciparum

BACKGROUND: DNA gyrase, an enzyme once thought to be unique to bacteria, is also found in some eukaryotic plastids including the apicoplast of Apicomplexa such as Plasmodium falciparum and Toxoplasma gondii which are important disease-causing organisms. DNA gyrase is an excellent target for antibact...

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Detalles Bibliográficos
Autores principales: Nagano, Soshichiro, Lin, Ting-Yu, Edula, Jyotheeswara Reddy, Heddle, Jonathan Gardiner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297366/
https://www.ncbi.nlm.nih.gov/pubmed/25523502
http://dx.doi.org/10.1186/s12859-014-0416-9