Cargando…

The role of Sox9 in mouse mammary gland development and maintenance of mammary stem and luminal progenitor cells

BACKGROUND: Identification and characterization of molecular controls that regulate mammary stem and progenitor cell homeostasis are critical to our understanding of normal mammary gland development and its pathology. RESULTS: We demonstrate that conditional knockout of Sox9 in the mouse mammary gla...

Descripción completa

Detalles Bibliográficos
Autores principales:	Malhotra, Gautam K, Zhao, Xiangshan, Edwards, Emily, Kopp, Janel L, Naramura, Mayumi, Sander, Maike, Band, Hamid, Band, Vimla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297388/ https://www.ncbi.nlm.nih.gov/pubmed/25527186 http://dx.doi.org/10.1186/s12861-014-0047-4

Ejemplares similares

Derivation of Myoepithelial Progenitor Cells from Bipotent Mammary Stem/Progenitor Cells
por: Zhao, Xiangshan, et al.
Publicado: (2012)

A block in lineage differentiation of immortal human mammary stem / progenitor cells by ectopically-expressed oncogenes
por: Zhao, Xiangshan, et al.
Publicado: (2011)

Distinct Effects of EGFR Ligands on Human Mammary Epithelial Cell Differentiation
por: Mukhopadhyay, Chandrani, et al.
Publicado: (2013)

A Comprehensive, Multi-Scale Dynamical Model of ErbB Receptor Signal Transduction in Human Mammary Epithelial Cells
por: Helikar, Tomáš, et al.
Publicado: (2013)

Mammary epithelial cell transformation: insights from cell culture and mouse models
por: Dimri, Goberdhan, et al.
Publicado: (2005)

Shared signaling pathways in normal and breast cancer stem cells
por: Malhotra, Gautam K., et al.
Publicado: (2011)

Luminal Progenitors Restrict Their Lineage Potential during Mammary Gland Development
por: Rodilla, Veronica, et al.
Publicado: (2015)

ADA3 regulates normal and tumor mammary epithelial cell proliferation through c-MYC
por: Griffin, Nicolas I., et al.
Publicado: (2016)

Kindlin-2 in myoepithelium controls luminal progenitor commitment to alveoli in mouse mammary gland
por: Wang, Zhenbin, et al.
Publicado: (2023)

The transcriptional repressor Blimp1 is expressed in rare luminal progenitors and is essential for mammary gland development
por: Ahmed, Mohammed I., et al.
Publicado: (2016)

Two functionally distinct epithelial progenitors exist within the luminal cell compartment of the mouse mammary gland
por: Stingl, J, et al.
Publicado: (2008)

The Luminal Progenitor Compartment of the Normal Human Mammary Gland Constitutes a Unique Site of Telomere Dysfunction
por: Kannan, Nagarajan, et al.
Publicado: (2013)

Id-1 is not expressed in the luminal epithelial cells of mammary glands
por: Uehara, Norihisa, et al.
Publicado: (2003)

Phenotypic and functional characterisation of the luminal cell hierarchy of the mammary gland
por: Shehata, Mona, et al.
Publicado: (2012)

Dachshund Depletion Disrupts Mammary Gland Development and Diverts the Composition of the Mammary Gland Progenitor Pool
por: Jiao, Xuanmao, et al.
Publicado: (2018)

Mechanisms of Trastuzumab resistance in ErbB2-driven breast cancer and newer opportunities to overcome therapy resistance
por: Bailey, Tameka A., et al.
Publicado: (2011)

Notch3 marks clonogenic mammary luminal progenitor cells in vivo
por: Lafkas, Daniel, et al.
Publicado: (2013)

Stat3 Is Required to Maintain the Full Differentiation Potential of Mammary Stem Cells and the Proliferative Potential of Mammary Luminal Progenitors
por: Staniszewska, Anna D., et al.
Publicado: (2012)

VANGL2 regulates luminal epithelial organization and cell turnover in the mammary gland
por: Smith, Prestina, et al.
Publicado: (2019)

Intratumoral Heterogeneity of Expression of 16 miRNA in Luminal Cancer of the Mammary Gland
por: Veryaskina, Yuliya A., et al.
Publicado: (2020)

Mutant Cbl proteins as oncogenic drivers in myeloproliferative disorders
por: Naramura, Mayumi, et al.
Publicado: (2011)

Genetic manipulation of the mammary gland by transplantation
por: Edwards, P
Publicado: (2003)

Cell type of origin as well as genetic alterations contribute to breast cancer phenotypes
por: Bhagirath, Divya, et al.
Publicado: (2015)

Mutant PIK3CA Induces EMT in a Cell Type Specific Manner
por: Bhagirath, Divya, et al.
Publicado: (2016)

The Mammary Gland Microenvironment Directs Progenitor Cell Fate In Vivo
por: Bussard, Karen M., et al.
Publicado: (2011)

Early lineage segregation of multipotent embryonic mammary gland progenitors
por: Wuidart, Aline, et al.
Publicado: (2018)

p53 controls the plasticity of mammary luminal progenitor cells downstream of Met signaling
por: Chiche, Aurélie, et al.
Publicado: (2019)

Mammary stem cells: angels or demons in mammary gland?
por: Chen, Xueman, et al.
Publicado: (2017)

Sox9 regulates cell state and activity of embryonic mouse mammary progenitor cells
por: Kogata, Naoko, et al.
Publicado: (2018)

Regulation of a progenitor gene program by SOX4 is essential for mammary tumor proliferation
por: Roukens, M. Guy, et al.
Publicado: (2021)

Tumors of the mammary gland
por: Rosen, Paul Peter
Publicado: (1993)

Mammary gland neoplasia.
por: Neumann, D A, et al.
Publicado: (1996)

Tuberculosis of the Mammary Gland
por: Goyle, Amar Nath, et al.
Publicado: (1935)

Tumor in Mammary Gland
Publicado: (1872)

Paracrine Met signaling triggers epithelial–mesenchymal transition in mammary luminal progenitors, affecting their fate
por: Di-Cicco, Amandine, et al.
Publicado: (2015)

Humanization of the mouse mammary gland by replacement of the luminal layer with genetically-engineered preneoplastic human cells
por: Verbeke, Stephanie, et al.
Publicado: (2014)

Vitamin D receptor regulates autophagy in the normal mammary gland and in luminal breast cancer cells
por: Tavera-Mendoza, Luz E., et al.
Publicado: (2017)

Characterization of Hyaluronan Localization in the Developing Mammary Gland and Mammary Tumors
por: Witschen, Patrice M., et al.
Publicado: (2023)

ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium
por: Holland, Daniel G, et al.
Publicado: (2011)

The transcription factor Sox10 is an essential determinant of branching morphogenesis and involution in the mouse mammary gland
por: Mertelmeyer, Svenja, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_0d8gi9ouhqd2bfquiilpa5gor4