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Protective immunity induced by peptides of AMA1, RON2 and RON4 containing T-and B-cell epitopes via an intranasal route against toxoplasmosis in mice
BACKGROUND: Toxoplasma gondii is a ubiquitous protozoan intracellular parasite, the causative agent of toxoplasmosis, and a worldwide zoonosis. Apical membrane antigen-1 (AMA1) and rhoptry neck protein (RON2, RON4) are involved in the invasion of T. gondii. METHODS: This study chemically synthesized...
Autores principales: | Zhang, Tie-E, Yin, Li-Tian, Li, Run-Hua, Wang, Hai-Long, Meng, Xiao-Li, Yin, Guo-Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297402/ https://www.ncbi.nlm.nih.gov/pubmed/25582167 http://dx.doi.org/10.1186/s13071-015-0636-5 |
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