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TDP-43 pathology in the basal forebrain and hypothalamus of patients with amyotrophic lateral sclerosis
INTRODUCTION: Amyotrophic lateral sclerosis is a neurodegenerative disease characterized clinically by motor symptoms including limb weakness, dysarthria, dysphagia, and respiratory compromise, and pathologically by inclusions of transactive response DNA-binding protein 43 kDa (TDP-43). Patients wit...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297460/ https://www.ncbi.nlm.nih.gov/pubmed/25539830 http://dx.doi.org/10.1186/s40478-014-0171-1 |