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Arsenic exposure is associated with DNA hypermethylation of the tumor suppressor gene p16
BACKGROUND: Occupational and environmental exposure to inorganic arsenic leads to development of cancer and represents a significant health hazard in more than 70 countries. The underlying mechanism for arsenic-induced carcinogenesis remains unclear. Laboratory studies suggest that arsenic is a poor...
Autores principales: | Lu, Guangming, Xu, Huiwen, Chang, De, Wu, Zhenglai, Yao, Xiaoyuan, Zhang, Shiying, Li, Zhenlong, Bai, Jieben, Cai, Qing, Zhang, Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297462/ https://www.ncbi.nlm.nih.gov/pubmed/25598836 http://dx.doi.org/10.1186/s12995-014-0042-5 |
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