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Comparing The Effects of Small Molecules BIX-01294, Bay K8644, RG-108 and Valproic Acid, and Their Different Combinations on Induction of Pluripotency Marker-Genes by Oct4 in The Mouse Brain

OBJECTIVE: Every cell type is characterized by a specific transcriptional profile together with a unique epigenetic landscape. Reprogramming factors such as Oct4, Klf4, Sox2 and c-Myc enable somatic cells to change their transcriptional profile and convert them to pluripotent cells. Small molecules...

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Detalles Bibliográficos
Autores principales:	Asadi, Sareh, Dehghan, Samaneh, Hajikaram, Maryam, Mowla, Seyed Javad, Ahmadiani, Abolhassan Ahmadiani, Javan, Mohammad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royan Institute 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297480/ https://www.ncbi.nlm.nih.gov/pubmed/25685732

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