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Successful Reprogramming of Epiblast Stem Cells by Blocking Nuclear Localization of β-Catenin

Epiblast stem cells (EpiSCs) in mice and rats are primed pluripotent stem cells (PSCs). They barely contribute to chimeric embryos when injected into blastocysts. Reprogramming of EpiSCs to embryonic stem cell (ESC)-like cells (rESCs) may occur in response to LIF-STAT3 signaling; however, low reprog...

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Detalles Bibliográficos
Autores principales:	Murayama, Hideyuki, Masaki, Hideki, Sato, Hideyuki, Hayama, Tomonari, Yamaguchi, Tomoyuki, Nakauchi, Hiromitsu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297867/ https://www.ncbi.nlm.nih.gov/pubmed/25556568 http://dx.doi.org/10.1016/j.stemcr.2014.12.003

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