Molecular Mechanisms Regulating the Defects in Fragile X Syndrome Neurons Derived from Human Pluripotent Stem Cells

Fragile X syndrome (FXS) is caused by the absence of the fragile X mental retardation protein (FMRP). We have previously generated FXS-induced pluripotent stem cells (iPSCs) from patients’ fibroblasts. In this study, we aimed at unraveling the molecular phenotype of the disease. Our data revealed ab...

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Detalles Bibliográficos
Autores principales: Halevy, Tomer, Czech, Christian, Benvenisty, Nissim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297868/
https://www.ncbi.nlm.nih.gov/pubmed/25483109
http://dx.doi.org/10.1016/j.stemcr.2014.10.015

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