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The role of reactive oxygen species (ROS) and cytochrome P-450 2E1 in the generation of carcinogenic etheno-DNA adducts

Exocyclic etheno-DNA adducts are mutagenic and carcinogenic and are formed by the reaction of lipidperoxidation (LPO) products such as 4-hydoxynonenal or malondialdehyde with DNA bases. LPO products are generated either via inflammation driven oxidative stress or via the induction of cytochrome P-45...

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Detalles Bibliográficos
Autores principales:	Linhart, Kirsten, Bartsch, Helmut, Seitz, Helmut K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Mini Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297928/ https://www.ncbi.nlm.nih.gov/pubmed/25462066 http://dx.doi.org/10.1016/j.redox.2014.08.009

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