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Peroxiredoxin 3 levels regulate a mitochondrial redox setpoint in malignant mesothelioma cells

Peroxiredoxin 3 (PRX3), a typical 2-Cys peroxiredoxin located exclusively in the mitochondrial matrix, is the principal peroxidase responsible for metabolizing mitochondrial hydrogen peroxide, a byproduct of cellular respiration originating from the mitochondrial electron transport chain. Mitochondr...

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Detalles Bibliográficos
Autores principales: Cunniff, Brian, Wozniak, Alexandra N., Sweeney, Patrick, DeCosta, Kendra, Heintz, Nicholas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297934/
https://www.ncbi.nlm.nih.gov/pubmed/25462069
http://dx.doi.org/10.1016/j.redox.2014.11.003