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Protein engineering to develop a redox insensitive endothelial nitric oxide synthase()

The zinc tetrathiolate (ZnS(4)) cluster is an important structural feature of endothelial nitric oxide synthase (eNOS). The cluster is located on the dimeric interface and four cysteine residues (C94 and C99 from two adjacent subunits) form a cluster with a Zn ion in the center of a tetrahedral conf...

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Detalles Bibliográficos
Autores principales:	Rafikov, Ruslan, Kumar, Sanjiv, Aggarwal, Saurabh, Pardo, Daniel, Fonseca, Fabio V., Ransom, Jessica, Rafikova, Olga, Chen, Qiumei, Springer, Matthew L., Black, Stephen M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297941/ https://www.ncbi.nlm.nih.gov/pubmed/25460726 http://dx.doi.org/10.1016/j.redox.2013.12.015

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