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Methodology to assay CYP2E1 mixed function oxidase catalytic activity and its induction

The cytochrome P450 mixed function oxidase enzymes are the major catalysts involved in drug metabolism. There are many forms of P450. CYP2E1 metabolizes many toxicologically important compounds including ethanol and is active in generating reactive oxygen species. Since several of the contributions...

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Detalles Bibliográficos
Autor principal: Cederbaum, Arthur I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297943/
https://www.ncbi.nlm.nih.gov/pubmed/25454746
http://dx.doi.org/10.1016/j.redox.2014.09.007