Cargando…

Novel recombinant chimeric virus-like particle is immunogenic and protective against both enterovirus 71 and coxsackievirus A16 in mice

Hand-foot-and-mouth disease (HFMD) has been recognized as an important global public health issue, which is predominantly caused by enterovirus 71 (EV-A71) and coxsackievirus A16 (CVA16). There is no available vaccine against HFMD. An ideal HFMD vaccine should be bivalent against both EV-A71 and CVA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Hui, Li, Hao-Yang, Han, Jian-Feng, Deng, Yong-Qiang, Zhu, Shun-Ya, Li, Xiao-Feng, Yang, Hui-Qin, Li, Yue-Xiang, Zhang, Yu, Qin, E-De, Chen, Rong, Qin, Cheng-Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297979/ https://www.ncbi.nlm.nih.gov/pubmed/25597595 http://dx.doi.org/10.1038/srep07878

Ejemplares similares

Seroepidemiology of human enterovirus71 and coxsackievirusA16 in Jiangsu province, China
por: Ji, Hong, et al.
Publicado: (2012)

Transcriptome analysis following enterovirus 71 and coxsackievirus A16 infection in respiratory epithelial cells
por: Song, Jie, et al.
Publicado: (2020)

Recombinant tandem multi-linear neutralizing epitopes of human enterovirus 71 elicited protective immunity in mice
por: Li, Yue-Xiang, et al.
Publicado: (2014)

Development of stable, cold-adapted, temperature-sensitive/conditional lethal chimeric enterovirus A71 and coxsackievirus A16
por: Chua, Kaw Bing, et al.
Publicado: (2022)

Seroepidemiology of human enterovirus71 and coxsackievirusA16 among children in Guangdong province, China
por: Li, Wei, et al.
Publicado: (2013)

VP1 of Enterovirus 71 Protects Mice Against Enterovirus 71 and Coxsackievirus B3 in Lethal Challenge Experiment
por: Chen, Fang-Hong, et al.
Publicado: (2019)

Co-Circulation and Genomic Recombination of Coxsackievirus A16 and Enterovirus 71 during a Large Outbreak of Hand, Foot, and Mouth Disease in Central China
por: Liu, Weiyong, et al.
Publicado: (2014)

Immunologic Characterization of Cytokine Responses to Enterovirus 71 and Coxsackievirus A16 Infection in Children
por: Zhang, Shu-Yan, et al.
Publicado: (2015)

Antiviral Ability of Kalanchoe gracilis Leaf Extract against Enterovirus 71 and Coxsackievirus A16
por: Wang, Ching-Ying, et al.
Publicado: (2012)

Comparing Enterovirus 71 with Coxsackievirus A16 by analyzing nucleotide sequences and antigenicity of recombinant proteins of VP1s and VP4s
por: Li, Yuyun, et al.
Publicado: (2011)

Seroepidemiology of Coxsackievirus A6, Coxsackievirus A16, and Enterovirus 71 Infections among Children and Adolescents in Singapore, 2008-2010
por: Ang, Li Wei, et al.
Publicado: (2015)

Bioinformatics-based prediction of conformational epitopes for Enterovirus A71 and Coxsackievirus A16
por: Wang, Liping, et al.
Publicado: (2021)

Seroprevalence of Enterovirus A71 and Coxsackievirus A16 in Healthy People in Shandong Province, China
por: Wang, Jian-xing, et al.
Publicado: (2016)

Detection of human enterovirus 71 and coxsackievirus A16 in children with hand, foot and mouth disease in China
por: CHEN, LING, et al.
Publicado: (2012)

Novel Substituted Heteroaromatic Piperazine and Piperidine Derivatives as Inhibitors of Human Enterovirus 71 and Coxsackievirus A16
por: Zhang, Xian, et al.
Publicado: (2013)

Seroprevalence of Human Enterovirus 71 and Coxsackievirus A16 in Guangdong, China, in Pre- and Post-2010 HFMD Epidemic Period
por: Li, Wei, et al.
Publicado: (2013)

Glycyrrhizic acid as the antiviral component of Glycyrrhiza uralensis Fisch. against coxsackievirus A16 and enterovirus 71 of hand foot and mouth disease
por: Wang, Jingjing, et al.
Publicado: (2013)

Computational Screening of Newly Designed Compounds against Coxsackievirus A16 and Enterovirus A71
por: Sripattaraphan, Amita, et al.
Publicado: (2022)

Global Transcriptomic Analysis of Human Neuroblastoma Cells in Response to Enterovirus Type 71 Infection
por: Xu, Li-Juan, et al.
Publicado: (2013)

Incorrect identification of recent Asian strains of Coxsackievirus A16 as human enterovirus 71: Improved primers for the specific detection of human enterovirus 71 by RT PCR
por: Perera, David, et al.
Publicado: (2004)

Complete genome analysis demonstrates multiple introductions of enterovirus 71 and coxsackievirus A16 recombinant strains into Thailand during the past decade
por: Noisumdaeng, Pirom, et al.
Publicado: (2018)

Systematic Identification and Bioinformatic Analysis of MicroRNAs in Response to Infections of Coxsackievirus A16 and Enterovirus 71
por: Zhu, Zheng, et al.
Publicado: (2016)

A Bivalent Inactivated Vaccine Prevents Enterovirus 71 and Coxsackievirus A16 Infections in the Mongolian Gerbil
por: Yi, Eun-Je, et al.
Publicado: (2023)

Pyroptosis induced by enterovirus 71 and coxsackievirus B3 infection affects viral replication and host response
por: Wang, Yan, et al.
Publicado: (2018)

Chimeric virus-like particles presenting common neutralizing epitopes of enterovirus 71
por: Wang, Bo, et al.
Publicado: (2011)

Recombinant Human Enterovirus 71
Publicado: (2004)

Identification of Luteolin as Enterovirus 71 and Coxsackievirus A16 Inhibitors through Reporter Viruses and Cell Viability-Based Screening
por: Xu, Lin, et al.
Publicado: (2014)

Human enterovirus 71 subgenotype B3 lacks coxsackievirus A16-like neurovirulence in mice infection
por: Chan, Yoke-Fun, et al.
Publicado: (2005)

Producing infectious enterovirus type 71 in a rapid strategy
por: Han, Jian-Feng, et al.
Publicado: (2010)

Serum MicroRNA Expression Profile Distinguishes Enterovirus 71 and Coxsackievirus 16 Infections in Patients with Hand-Foot-and-Mouth Disease
por: Cui, Lunbiao, et al.
Publicado: (2011)

Circulating Coxsackievirus A16 Identified as Recombinant Type A Human Enterovirus, China
por: Zhao, Ke, et al.
Publicado: (2011)

Evaluation of human enterovirus 71 and coxsackievirus A16 specific immunoglobulin M antibodies for diagnosis of hand-foot-and-mouth disease
por: Yu, Nan, et al.
Publicado: (2012)

Antibody dependent enhancement infection of Enterovirus 71 in vitro and in vivo
por: Han, Jian-Feng, et al.
Publicado: (2011)

Substitution of Coxsackievirus A16 VP1 BC and EF Loop Altered the Protective Immune Responses in Chimera Enterovirus A71
por: Tan, Xiu Hui, et al.
Publicado: (2023)

Development of a multiplex polymerase chain reaction assay for simultaneous identification of human enterovirus 71 and coxsackievirus A16
por: Thao, Nguyen Thi Thanh, et al.
Publicado: (2010)

Potent antiviral agents fail to elicit genetically-stable resistance mutations in either enterovirus 71 or Coxsackievirus A16
por: Kelly, James T., et al.
Publicado: (2015)

Molecular evolutionary dynamics of enterovirus A71, coxsackievirus A16 and coxsackievirus A6 causing hand, foot and mouth disease in Thailand, 2000–2022
por: Noisumdaeng, Pirom, et al.
Publicado: (2023)

Applicability of duplex real time and lateral flow strip reverse-transcription recombinase aided amplification assays for the detection of Enterovirus 71 and Coxsackievirus A16
por: Li, Xin-na, et al.
Publicado: (2019)

Estimation of Basic Reproduction Number of Enterovirus 71, Coxsackievirus A6 and A16 in Hand, Foot, and Mouth Disease Outbreaks in Singapore
por: Lim, Cindy, et al.
Publicado: (2014)

Clinical characteristics and managements of severe hand, foot and mouth disease caused by enterovirus A71 and coxsackievirus A16 in Shanghai, China
por: Cai, Kang, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_e5viprmksblqbhfo33odth5mh0