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A novel software program for detection of potential air emboli during cardiac surgery
BACKGROUND: Risks associated with air emboli introduced during cardiac surgery have been highlighted by reports of postoperative neuropsychological dysfunction, myocardial dysfunction, and mortality. Presently, there are no standard effective methods for quantifying potential emboli in the bloodstre...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298052/ https://www.ncbi.nlm.nih.gov/pubmed/25582221 http://dx.doi.org/10.1186/1476-7120-13-3 |
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author | Secretain, Frank Pollard, Andrew Uddin, Mesbah Ball, Christopher G Hamilton, Andrew Tanzola, Robert C Thorpe, Joelle B Milne, Brian |
author_facet | Secretain, Frank Pollard, Andrew Uddin, Mesbah Ball, Christopher G Hamilton, Andrew Tanzola, Robert C Thorpe, Joelle B Milne, Brian |
author_sort | Secretain, Frank |
collection | PubMed |
description | BACKGROUND: Risks associated with air emboli introduced during cardiac surgery have been highlighted by reports of postoperative neuropsychological dysfunction, myocardial dysfunction, and mortality. Presently, there are no standard effective methods for quantifying potential emboli in the bloodstream during cardiac surgery. Our objective was to develop software that can automatically detect and quantify air bubbles within the ascending aorta and/or cardiac chambers during cardiac surgery in real time. FINDINGS: We created a software algorithm (“Detection of Emboli using Transesophageal Echocardiography for Counting, Total volume, and Size estimation”, or DETECTS™) to identify and measure potential emboli present during cardiac surgery using two-dimensional ultrasound. An in vitro experiment was used to validate the accuracy of DETECTS™ at identifying and measuring air emboli. An experimental rig was built to correlate the ultrasound images to high definition camera images of air bubbles created in water by an automatic bubbler system. There was a correlation between true bubble size and the size reported by DETECTS™ in our in vitro experiment (r = 0.76). We also tested DETECTS™ using TEE images obtained during cardiac surgery, and provide visualization of the software interface. CONCLUSIONS: While monitoring the heart during cardiac surgery using existing ultrasound technology and DETECTS™, the operative team can obtain real-time data on the number and volume of potential air emboli. This system will potentially allow de-airing techniques to be evaluated and improved upon. This could lead to reduced air in the cardiac chambers after cardiopulmonary bypass, possibly reducing the risk of neurological dysfunction following cardiac surgery. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1476-7120-13-3) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-4298052 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-42980522015-01-20 A novel software program for detection of potential air emboli during cardiac surgery Secretain, Frank Pollard, Andrew Uddin, Mesbah Ball, Christopher G Hamilton, Andrew Tanzola, Robert C Thorpe, Joelle B Milne, Brian Cardiovasc Ultrasound Technical Notes BACKGROUND: Risks associated with air emboli introduced during cardiac surgery have been highlighted by reports of postoperative neuropsychological dysfunction, myocardial dysfunction, and mortality. Presently, there are no standard effective methods for quantifying potential emboli in the bloodstream during cardiac surgery. Our objective was to develop software that can automatically detect and quantify air bubbles within the ascending aorta and/or cardiac chambers during cardiac surgery in real time. FINDINGS: We created a software algorithm (“Detection of Emboli using Transesophageal Echocardiography for Counting, Total volume, and Size estimation”, or DETECTS™) to identify and measure potential emboli present during cardiac surgery using two-dimensional ultrasound. An in vitro experiment was used to validate the accuracy of DETECTS™ at identifying and measuring air emboli. An experimental rig was built to correlate the ultrasound images to high definition camera images of air bubbles created in water by an automatic bubbler system. There was a correlation between true bubble size and the size reported by DETECTS™ in our in vitro experiment (r = 0.76). We also tested DETECTS™ using TEE images obtained during cardiac surgery, and provide visualization of the software interface. CONCLUSIONS: While monitoring the heart during cardiac surgery using existing ultrasound technology and DETECTS™, the operative team can obtain real-time data on the number and volume of potential air emboli. This system will potentially allow de-airing techniques to be evaluated and improved upon. This could lead to reduced air in the cardiac chambers after cardiopulmonary bypass, possibly reducing the risk of neurological dysfunction following cardiac surgery. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1476-7120-13-3) contains supplementary material, which is available to authorized users. BioMed Central 2015-01-12 /pmc/articles/PMC4298052/ /pubmed/25582221 http://dx.doi.org/10.1186/1476-7120-13-3 Text en © Secretain et al.; licensee BioMed Central. 2015 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Technical Notes Secretain, Frank Pollard, Andrew Uddin, Mesbah Ball, Christopher G Hamilton, Andrew Tanzola, Robert C Thorpe, Joelle B Milne, Brian A novel software program for detection of potential air emboli during cardiac surgery |
title | A novel software program for detection of potential air emboli during cardiac surgery |
title_full | A novel software program for detection of potential air emboli during cardiac surgery |
title_fullStr | A novel software program for detection of potential air emboli during cardiac surgery |
title_full_unstemmed | A novel software program for detection of potential air emboli during cardiac surgery |
title_short | A novel software program for detection of potential air emboli during cardiac surgery |
title_sort | novel software program for detection of potential air emboli during cardiac surgery |
topic | Technical Notes |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298052/ https://www.ncbi.nlm.nih.gov/pubmed/25582221 http://dx.doi.org/10.1186/1476-7120-13-3 |
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