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Protective Role for Caspase-11 during Acute Experimental Murine Colitis
Activation of the noncanonical inflammasome, mediated by caspase-11, serves as an additional pathway for the production of the proinflammatory cytokines IL-1β and IL-18. Noncanonical inflammasome activity occurs during host defense against Gram-negative bacteria and in models of acute septic shock....
Autores principales: | Oficjalska, Katarzyna, Raverdeau, Mathilde, Aviello, Gabriella, Wade, Siobhan C., Hickey, Ana, Sheehan, Katherine M., Corr, Sinead C., Kay, Elaine W., O’Neill, Luke A., Mills, Kingston H. G., Creagh, Emma M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298125/ https://www.ncbi.nlm.nih.gov/pubmed/25548224 http://dx.doi.org/10.4049/jimmunol.1400501 |
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