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Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2
Altered epidermal differentiation characterizes numerous skin diseases affecting >25% of the human population. Here we identified Fra-2/AP-1 as a key regulator of terminal epidermal differentiation. Epithelial-restricted, ectopic expression of Fra-2 induced expression of epidermal differentiation...
Autores principales: | Wurm, Stefanie, Zhang, Jisheng, Guinea-Viniegra, Juan, García, Fernando, Muñoz, Javier, Bakiri, Latifa, Ezhkova, Elena, Wagner, Erwin F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298134/ https://www.ncbi.nlm.nih.gov/pubmed/25547114 http://dx.doi.org/10.1101/gad.249748.114 |
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