ATDC induces an invasive switch in KRAS-induced pancreatic tumorigenesis

The initiation of pancreatic ductal adenocarcinoma (PDA) is linked to activating mutations in KRAS. However, in PDA mouse models, expression of oncogenic mutant KRAS during development gives rise to tumors only after a prolonged latency or following induction of pancreatitis. Here we describe a nove...

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Detalles Bibliográficos
Autores principales: Wang, Lidong, Yang, Huibin, Abel, Ethan V., Ney, Gina M., Palmbos, Phillip L., Bednar, Filip, Zhang, Yaqing, Leflein, Jacob, Waghray, Meghna, Owens, Scott, Wilkinson, John E., Prasad, Jayendra, Ljungman, Mats, Rhim, Andrew D., Pasca di Magliano, Marina, Simeone, Diane M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298136/
https://www.ncbi.nlm.nih.gov/pubmed/25593307
http://dx.doi.org/10.1101/gad.253591.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298136/
https://www.ncbi.nlm.nih.gov/pubmed/25593307
http://dx.doi.org/10.1101/gad.253591.114

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