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FBXL20-mediated Vps34 ubiquitination as a p53 controlled checkpoint in regulating autophagy and receptor degradation

Vacuolar protein-sorting 34 (Vps34), the catalytic subunit in the class III PtdIns3 (phosphatidylinositol 3) kinase complexes, mediates the production of PtdIns3P, a key intracellular lipid involved in regulating autophagy and receptor degradation. However, the signal transduction pathways by which...

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Detalles Bibliográficos
Autores principales:	Xiao, Juan, Zhang, Tao, Xu, Daichao, Wang, Huibing, Cai, Yu, Jin, Taijie, Liu, Min, Jin, Mingzhi, Wu, Kejia, Yuan, Junying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298137/ https://www.ncbi.nlm.nih.gov/pubmed/25593308 http://dx.doi.org/10.1101/gad.252528.114

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